Explore NTSR2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T95605
|
| Target Name |
NTSR2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
23620
|
| Gene ID |
100072278 (Equus caballus), 101093768 (Felis catus), 18217 (Mus musculus), 23620 (Homo sapiens)
482972 (Canis lupus familiaris), 539336 (Bos taurus), 64636 (Rattus norvegicus), 697563 (Macaca mulatta)
|
| Target Alternative Names |
Levocabastine-sensitive neurotensin receptor,NT-R-2,NT2R,NTR2,NTRL,NTSR2,Neurotensin receptor type 2,Ntsr2
|
| Uniprot Accession |
P70310,O95665,Q63384
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction
|
| Gene Ensembl |
ENSECAG00000016454, ENSMUSG00000020591, ENSG00000169006, ENSCAFG00845028451, ENSBTAG00000003691, ENSMMUG00000020250
|
NTSR2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo23620 | Pre-made Human NTSR2/NTR2 siRNA oligo Duplex | 23620 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo64636 | Pre-made Rat Ntsr2 siRNA oligo Duplex | 64636 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18217 | Pre-made Mouse Ntsr2/NT2R/NTR2 siRNA oligo Duplex | 18217 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo697563 | Pre-made Cynomolgus/Rhesus macaque NTSR2 siRNA oligo Duplex | 697563 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093768 | Pre-made Cat/Feline NTSR2 siRNA oligo Duplex | 101093768 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482972 | Pre-made Dog/Canine NTSR2 siRNA oligo Duplex | 482972 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539336 | Pre-made Bovines/Cattle NTSR2 siRNA oligo Duplex | 539336 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072278 | Pre-made Equine/Horse NTSR2 siRNA oligo Duplex | 100072278 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NTSR2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T95605-Ab | Human | Anti-Human NTSR2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-T95605-Ab | Rat | Anti-Rat NTSR2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-T95605-Ab | Mouse | Anti-Mouse NTSR2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-T95605-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NTSR2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-T95605-Ab | Cat/Feline | Anti-Cat/Feline NTSR2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-T95605-Ab | Dog/Canine | Anti-Dog/Canine NTSR2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-T95605-Ab | Bovines/Cattle | Anti-Bovines/Cattle NTSR2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-T95605-Ab | Equine/Horse | Anti-Equine/Horse NTSR2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
NTSR2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T95605-Ag | Human | Human NTSR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T95605-Ag | Rat | Rat NTSR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T95605-Ag | Mouse | Mouse NTSR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T95605-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NTSR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T95605-Ag | Cat/Feline | Cat/Feline NTSR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T95605-Ag | Dog/Canine | Dog/Canine NTSR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T95605-Ag | Bovines/Cattle | Bovines/Cattle NTSR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T95605-Ag | Equine/Horse | Equine/Horse NTSR2 VLP (virus-like particle) | HEK293 | Products Developing |
