Explore EAAT2/SLC1A2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Improper regulation of this gene is thought to be associated with several neurological disorders. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2017]
| Target ID |
GM-T95438
|
| Target Name |
EAAT2/SLC1A2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6506
|
| Gene ID |
100067133 (Equus caballus), 20511 (Mus musculus), 29482 (Rattus norvegicus), 403750 (Canis lupus familiaris)
493929 (Felis catus), 541119 (Bos taurus), 574358 (Macaca mulatta), 6506 (Homo sapiens)
|
| Target Alternative Names |
1700091C19Rik,2900019G14Rik,DEE41,EAAT2,EIEE41,Eaat2,Excitatory amino acid transporter 2,GLT-1,GLT1,Glt,Glt-1,Glutamate/aspartate transporter II,HBGT,MGLT1,SLC1A2,Slc1a2,Sodium-dependent glutamate/aspartate transporter 2,Solute carrier family 1 member 2
|
| Uniprot Accession |
P43006,P31596,P43004
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Glutamatergic synapse
|
| Gene Ensembl |
ENSECAG00000015644, ENSMUSG00000005089, ENSCAFG00845021493, ENSBTAG00000012628, ENSMMUG00000004329, ENSG00000110436
|
Pre-made viral vector of EAAT2/SLC1A2 cDNA Clones/ORF Plasmid
EAAT2/SLC1A2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6506 | Pre-made Human SLC1A2/GLT1/HBGT siRNA oligo Duplex | 6506 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29482 | Pre-made Rat Slc1a2/Glt/Eaat2 siRNA oligo Duplex | 29482 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20511 | Pre-made Mouse Slc1a2/GLT1/Eaat2 siRNA oligo Duplex | 20511 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574358 | Pre-made Cynomolgus/Rhesus macaque SLC1A2 siRNA oligo Duplex | 574358 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493929 | Pre-made Cat/Feline SLC1A2/GLT1/EAAT2 siRNA oligo Duplex | 493929 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403750 | Pre-made Dog/Canine SLC1A2/GLT1 siRNA oligo Duplex | 403750 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo541119 | Pre-made Bovines/Cattle SLC1A2 siRNA oligo Duplex | 541119 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100067133 | Pre-made Equine/Horse SLC1A2 siRNA oligo Duplex | 100067133 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EAAT2/SLC1A2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T95438-Ab | Human | Anti-Human EAAT2/SLC1A2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T95438-Ab | Rat | Anti-Rat EAAT2/SLC1A2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T95438-Ab | Mouse | Anti-Mouse EAAT2/SLC1A2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T95438-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EAAT2/SLC1A2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T95438-Ab | Cat/Feline | Anti-Cat/Feline EAAT2/SLC1A2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T95438-Ab | Dog/Canine | Anti-Dog/Canine EAAT2/SLC1A2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T95438-Ab | Bovines/Cattle | Anti-Bovines/Cattle EAAT2/SLC1A2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T95438-Ab | Equine/Horse | Anti-Equine/Horse EAAT2/SLC1A2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
EAAT2/SLC1A2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T95438-Ag | Human | Human EAAT2/SLC1A2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T95438-Ag | Rat | Rat EAAT2/SLC1A2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T95438-Ag | Mouse | Mouse EAAT2/SLC1A2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T95438-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EAAT2/SLC1A2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T95438-Ag | Cat/Feline | Cat/Feline EAAT2/SLC1A2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T95438-Ag | Dog/Canine | Dog/Canine EAAT2/SLC1A2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T95438-Ag | Bovines/Cattle | Bovines/Cattle EAAT2/SLC1A2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T95438-Ag | Equine/Horse | Equine/Horse EAAT2/SLC1A2 VLP (virus-like particle) | HEK293 | Products Developing |
