Explore IFNAR1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor. [provided by RefSeq, Jul 2020]
| Target ID |
GM-T95371
|
| Target Name |
IFNAR1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3454
|
| Gene ID |
100063402 (Equus caballus), 101092535 (Felis catus), 15975 (Mus musculus), 282257 (Bos taurus)
288264 (Rattus norvegicus), 3454 (Homo sapiens), 609830 (Canis lupus familiaris), 699604 (Macaca mulatta)
|
| Target Alternative Names |
AVP,Cytokine receptor class-II member 1,Cytokine receptor family 2 member 1 (CRF2-1),IFN-R-1,IFN-alpha-REC,IFN-alpha/beta receptor 1,IFNAR,IFNAR1,IFNBR,IFRC,IMD106,Ifar,Ifnar,Ifnar1,Ifrc,Infar,Interferon alpha/beta receptor 1,Type I interferon receptor 1
|
| Uniprot Accession |
P33896,Q04790,P17181
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, Osteoclast differentiation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Hepatitis C, Hepatitis B, Measles, Influenza A, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Epstein-Barr virus infection, Pathways in cancer
|
| Gene Ensembl |
ENSECAG00000010260, ENSMUSG00000022967, ENSBTAG00000021819, ENSG00000142166, ENSCAFG00845026778, ENSMMUG00000003961
|
| Target Classification |
Cytokine Receptor, Checkpoint-Immuno Oncology
|
Pre-made viral vector of IFNAR1 cDNA Clones/ORF Plasmid
IFNAR1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3454 | Pre-made Human IFNAR1/AVP/IFRC siRNA oligo Duplex | 3454 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo288264 | Pre-made Rat Ifnar1 siRNA oligo Duplex | 288264 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15975 | Pre-made Mouse Ifnar1/Ifar/Ifrc siRNA oligo Duplex | 15975 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699604 | Pre-made Cynomolgus/Rhesus macaque IFNAR1 siRNA oligo Duplex | 699604 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092535 | Pre-made Cat/Feline IFNAR1 siRNA oligo Duplex | 101092535 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo609830 | Pre-made Dog/Canine IFNAR1 siRNA oligo Duplex | 609830 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282257 | Pre-made Bovines/Cattle IFNAR1 siRNA oligo Duplex | 282257 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100063402 | Pre-made Equine/Horse IFNAR1 siRNA oligo Duplex | 100063402 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IFNAR1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T95371-Ab | Human | Anti-Human IFNAR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T95371-Ab | Rat | Anti-Rat IFNAR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T95371-Ab | Mouse | Anti-Mouse IFNAR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T95371-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IFNAR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T95371-Ab | Cat/Feline | Anti-Cat/Feline IFNAR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T95371-Ab | Dog/Canine | Anti-Dog/Canine IFNAR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T95371-Ab | Bovines/Cattle | Anti-Bovines/Cattle IFNAR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T95371-Ab | Equine/Horse | Anti-Equine/Horse IFNAR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
IFNAR1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T95371-Ag | Human | Human IFNAR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T95371-Ag | Rat | Rat IFNAR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T95371-Ag | Mouse | Mouse IFNAR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T95371-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IFNAR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T95371-Ag | Cat/Feline | Cat/Feline IFNAR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T95371-Ag | Dog/Canine | Dog/Canine IFNAR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T95371-Ag | Bovines/Cattle | Bovines/Cattle IFNAR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T95371-Ag | Equine/Horse | Equine/Horse IFNAR1 VLP (virus-like particle) | HEK293 | Products Developing |
