Explore TYRO3 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses. [provided by RefSeq, May 2010]
| Target ID |
GM-T94880
|
| Target Name |
TYRO3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7301
|
| Gene ID |
100071144 (Equus caballus), 101083854 (Felis catus), 22174 (Mus musculus), 25232 (Rattus norvegicus)
487509 (Canis lupus familiaris), 710902 (Macaca mulatta), 7301 (Homo sapiens), 788224 (Bos taurus)
|
| Target Alternative Names |
BYK,Brt,Dtk,Etk-2,RSE,Rek,Rse,Sky,TK19-2,TYRO3,Tif,Tyro3,Tyrosine-protein kinase BYK,Tyrosine-protein kinase DTK,Tyrosine-protein kinase RSE,Tyrosine-protein kinase SKY,Tyrosine-protein kinase TIF,Tyrosine-protein kinase receptor TYRO3,etk2/tyro3,tk19-1
|
| Uniprot Accession |
P55144,P55146,Q06418
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000017862, ENSMUSG00000027298, ENSCAFG00845030075, ENSMMUG00000013803, ENSG00000092445, ENSBTAG00000001694
|
| Target Classification |
Kinase, Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
Pre-made viral vector of TYRO3 cDNA Clones/ORF Plasmid
TYRO3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7301 | Pre-made Human TYRO3/BYK/Dtk siRNA oligo Duplex | 7301 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25232 | Pre-made Rat Tyro3/Brt siRNA oligo Duplex | 25232 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo22174 | Pre-made Mouse Tyro3/Brt/Dtk siRNA oligo Duplex | 22174 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710902 | Pre-made Cynomolgus/Rhesus macaque TYRO3 siRNA oligo Duplex | 710902 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083854 | Pre-made Cat/Feline TYRO3 siRNA oligo Duplex | 101083854 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487509 | Pre-made Dog/Canine TYRO3 siRNA oligo Duplex | 487509 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo788224 | Pre-made Bovines/Cattle TYRO3 siRNA oligo Duplex | 788224 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100071144 | Pre-made Equine/Horse TYRO3 siRNA oligo Duplex | 100071144 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TYRO3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T94880-Ab | Human | Anti-Human TYRO3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T94880-Ab | Rat | Anti-Rat TYRO3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T94880-Ab | Mouse | Anti-Mouse TYRO3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T94880-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TYRO3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T94880-Ab | Cat/Feline | Anti-Cat/Feline TYRO3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T94880-Ab | Dog/Canine | Anti-Dog/Canine TYRO3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T94880-Ab | Bovines/Cattle | Anti-Bovines/Cattle TYRO3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T94880-Ab | Equine/Horse | Anti-Equine/Horse TYRO3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
TYRO3 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T94880-Ag | Human | Human TYRO3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T94880-Ag | Rat | Rat TYRO3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T94880-Ag | Mouse | Mouse TYRO3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T94880-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TYRO3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T94880-Ag | Cat/Feline | Cat/Feline TYRO3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T94880-Ag | Dog/Canine | Dog/Canine TYRO3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T94880-Ag | Bovines/Cattle | Bovines/Cattle TYRO3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T94880-Ag | Equine/Horse | Equine/Horse TYRO3 VLP (virus-like particle) | HEK293 | Products Developing |
