Explore PNLIP/Pancreatic Lipase gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the lipase family of proteins. The encoded enzyme is secreted by the pancreas and hydrolyzes triglycerides in the small intestine, and is essential for the efficient digestion of dietary fats. Inhibition of the encoded enzyme may prevent high-fat diet-induced obesity in mice and result in weight loss in human patients with obesity. Mutations in this gene cause congenital pancreatic lipase deficiency, a rare disorder characterized by steatorrhea. [provided by RefSeq, Jul 2016]
| Target ID |
GM-T94309
|
| Target Name |
PNLIP/Pancreatic Lipase
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5406
|
| Gene ID |
101083211 (Felis catus), 25702 (Rattus norvegicus), 477830 (Canis lupus familiaris), 5406 (Homo sapiens)
69060 (Mus musculus), 706689 (Macaca mulatta)
|
| Target Alternative Names |
1810007A24Rik,PANLI,PL,PNLIP,PNLIPD,PTL,Pancreatic Lipase,Pancreatic lipase,Pancreatic triacylglycerol lipase,Pnlip
|
| Uniprot Accession |
P27657,P16233,Q6P8U6
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, Pancreatic secretion, Fat digestion and absorption, Vitamin digestion and absorption
|
| Gene Ensembl |
ENSCAFG00845030995, ENSG00000175535, ENSMUSG00000046008, ENSMMUG00000000148
|
Pre-made viral vector of PNLIP/Pancreatic Lipase cDNA Clones/ORF Plasmid
PNLIP/Pancreatic Lipase siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5406 | Pre-made Human PNLIP/PL/PTL siRNA oligo Duplex | 5406 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25702 | Pre-made Rat Pnlip/PANLI siRNA oligo Duplex | 25702 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo69060 | Pre-made Mouse Pnlip/PL/PTL siRNA oligo Duplex | 69060 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706689 | Pre-made Cynomolgus/Rhesus macaque PNLIP siRNA oligo Duplex | 706689 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083211 | Pre-made Cat/Feline PNLIP/PL/PTL siRNA oligo Duplex | 101083211 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477830 | Pre-made Dog/Canine PNLIP siRNA oligo Duplex | 477830 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
PNLIP/Pancreatic Lipase antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T94309-Ab | Human | Anti-Human PNLIP/Pancreatic Lipase monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T94309-Ab | Rat | Anti-Rat PNLIP/Pancreatic Lipase monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T94309-Ab | Mouse | Anti-Mouse PNLIP/Pancreatic Lipase monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T94309-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PNLIP/Pancreatic Lipase monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T94309-Ab | Cat/Feline | Anti-Cat/Feline PNLIP/Pancreatic Lipase monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T94309-Ab | Dog/Canine | Anti-Dog/Canine PNLIP/Pancreatic Lipase monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
PNLIP/Pancreatic Lipase recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T94309-Ag | Human | Human PNLIP/Pancreatic Lipase recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T94309-Ag | Rat | Rat PNLIP/Pancreatic Lipase recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T94309-Ag | Mouse | Mouse PNLIP/Pancreatic Lipase recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T94309-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PNLIP/Pancreatic Lipase recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T94309-Ag | Cat/Feline | Cat/Feline PNLIP/Pancreatic Lipase recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T94309-Ag | Dog/Canine | Dog/Canine PNLIP/Pancreatic Lipase recombinant protein | Mammalian cell | Detail |
