Explore TNFRSF9/CD137 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T93923
|
| Target Name |
TNFRSF9/CD137
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3604
|
| Gene ID |
100058657 (Equus caballus), 101096582 (Felis catus), 21942 (Mus musculus), 3604 (Homo sapiens)
500590 (Rattus norvegicus), 520341 (Bos taurus), 608274 (Canis lupus familiaris), 708281 (Macaca mulatta)
|
| Target Alternative Names |
4-1BB,4-1BB ligand receptor,A930040I11Rik,CD137,CDw137,Cd137,ILA,IMD109,Ly63,T-cell antigen 4-1BB homolog,T-cell antigen ILA,TNFRSF9,Tnfrsf9,Tumor necrosis factor receptor superfamily member 9
|
| Uniprot Accession |
P20334,Q07011
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction
|
| Gene Ensembl |
ENSECAG00000057893, ENSMUSG00000028965, ENSG00000049249, ENSBTAG00000003313, ENSCAFG00845027358, ENSMMUG00000016546
|
| Target Classification |
Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
Pre-made viral vector of TNFRSF9/CD137 cDNA Clones/ORF Plasmid
TNFRSF9/CD137 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3604 | Pre-made Human TNFRSF9/ILA/4-1BB siRNA oligo Duplex | 3604 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo500590 | Pre-made Rat Tnfrsf9/4-1BB siRNA oligo Duplex | 500590 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21942 | Pre-made Mouse Tnfrsf9/ILA/Ly63 siRNA oligo Duplex | 21942 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708281 | Pre-made Cynomolgus/Rhesus macaque TNFRSF9 siRNA oligo Duplex | 708281 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096582 | Pre-made Cat/Feline TNFRSF9 siRNA oligo Duplex | 101096582 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo608274 | Pre-made Dog/Canine TNFRSF9 siRNA oligo Duplex | 608274 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo520341 | Pre-made Bovines/Cattle TNFRSF9 siRNA oligo Duplex | 520341 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058657 | Pre-made Equine/Horse TNFRSF9 siRNA oligo Duplex | 100058657 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TNFRSF9/CD137 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T93923-Ab | Human | Anti-Human TNFRSF9/CD137 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T93923-Ab | Rat | Anti-Rat TNFRSF9/CD137 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T93923-Ab | Mouse | Anti-Mouse TNFRSF9/CD137 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T93923-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TNFRSF9/CD137 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T93923-Ab | Cat/Feline | Anti-Cat/Feline TNFRSF9/CD137 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T93923-Ab | Dog/Canine | Anti-Dog/Canine TNFRSF9/CD137 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T93923-Ab | Bovines/Cattle | Anti-Bovines/Cattle TNFRSF9/CD137 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T93923-Ab | Equine/Horse | Anti-Equine/Horse TNFRSF9/CD137 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
TNFRSF9/CD137 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T93923-Ag | Human | Human TNFRSF9/CD137 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T93923-Ag | Rat | Rat TNFRSF9/CD137 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T93923-Ag | Mouse | Mouse TNFRSF9/CD137 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T93923-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TNFRSF9/CD137 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T93923-Ag | Cat/Feline | Cat/Feline TNFRSF9/CD137 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T93923-Ag | Dog/Canine | Dog/Canine TNFRSF9/CD137 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T93923-Ag | Bovines/Cattle | Bovines/Cattle TNFRSF9/CD137 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T93923-Ag | Equine/Horse | Equine/Horse TNFRSF9/CD137 VLP (virus-like particle) | HEK293 | Products Developing |
