Explore CNGA1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is involved in phototransduction. Along with another protein, the encoded protein forms a cGMP-gated cation channel in the plasma membrane, allowing depolarization of rod photoreceptors. This represents the last step in the phototransduction pathway. Defects in this gene are a cause of retinitis pigmentosa autosomal recessive (ARRP) disease. Multiple transcript variants have been found for this gene. [provided by RefSeq, Oct 2019]
| Target ID |
GM-T93798
|
| Target Name |
CNGA1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1259
|
| Gene ID |
100061553 (Equus caballus), 101096230 (Felis catus), 1259 (Homo sapiens), 12788 (Mus musculus)
281700 (Bos taurus), 403891 (Canis lupus familiaris), 704891 (Macaca mulatta), 85259 (Rattus norvegicus)
|
| Target Alternative Names |
CNCG,CNCG1,CNG,CNG channel alpha-1,CNG-1,CNG1,CNGA1,CNGC1,Cncg,Cnga1,Cyclic nucleotide-gated channel,Cyclic nucleotide-gated channel alpha-1,HCN,RCNC1,RCNCa,RCNCalpha,RP49,Rod photoreceptor cGMP-gated cation channel subunit alpha,cGMP-gated cation channel alpha-1,photoreceptor
|
| Uniprot Accession |
P29973,P29974,Q00194,Q28279,Q62927
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
cGMP-PKG signaling pathway, cAMP signaling pathway
|
| Gene Ensembl |
ENSECAG00000020953, ENSG00000198515, ENSMUSG00000067220, ENSBTAG00000002205, ENSCAFG00845009629, ENSMMUG00000005764
|
Pre-made viral vector of CNGA1 cDNA Clones/ORF Plasmid
CNGA1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1259 | Pre-made Human CNGA1/CNCG/CNG1 siRNA oligo Duplex | 1259 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo85259 | Pre-made Rat Cnga1/HCN/Cncg siRNA oligo Duplex | 85259 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12788 | Pre-made Mouse Cnga1/Cncg siRNA oligo Duplex | 12788 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704891 | Pre-made Cynomolgus/Rhesus macaque CNGA1 siRNA oligo Duplex | 704891 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096230 | Pre-made Cat/Feline CNGA1 siRNA oligo Duplex | 101096230 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403891 | Pre-made Dog/Canine CNGA1/CNGC1 siRNA oligo Duplex | 403891 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281700 | Pre-made Bovines/Cattle CNGA1/CNG/CNCG1 siRNA oligo Duplex | 281700 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100061553 | Pre-made Equine/Horse CNGA1 siRNA oligo Duplex | 100061553 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CNGA1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T93798-Ab | Human | Anti-Human CNGA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T93798-Ab | Rat | Anti-Rat CNGA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T93798-Ab | Mouse | Anti-Mouse CNGA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T93798-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CNGA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T93798-Ab | Cat/Feline | Anti-Cat/Feline CNGA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T93798-Ab | Dog/Canine | Anti-Dog/Canine CNGA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T93798-Ab | Bovines/Cattle | Anti-Bovines/Cattle CNGA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T93798-Ab | Equine/Horse | Anti-Equine/Horse CNGA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CNGA1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T93798-Ag | Human | Human CNGA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T93798-Ag | Rat | Rat CNGA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T93798-Ag | Mouse | Mouse CNGA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T93798-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CNGA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T93798-Ag | Cat/Feline | Cat/Feline CNGA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T93798-Ag | Dog/Canine | Dog/Canine CNGA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T93798-Ag | Bovines/Cattle | Bovines/Cattle CNGA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T93798-Ag | Equine/Horse | Equine/Horse CNGA1 VLP (virus-like particle) | HEK293 | Products Developing |
