Explore EDG2/LPAR1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Many transcript variants encoding a few different isoforms have been identified for this gene. [provided by RefSeq, Oct 2020]
| Target ID |
GM-T92640
|
| Target Name |
EDG2/LPAR1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1902
|
| Gene ID |
100053797 (Equus caballus), 101092556 (Felis catus), 116744 (Rattus norvegicus), 14745 (Mus musculus)
1902 (Homo sapiens), 281136 (Bos taurus), 474800 (Canis lupus familiaris), 709208 (Macaca mulatta)
|
| Target Alternative Names |
EDG2,Edg2,Gpcr26,Kdt2,LPA receptor 1,LPA-1,LPA1,LPAR1,Lpar1,Lysophosphatidic acid receptor 1,Lysophosphatidic acid receptor Edg-2,Mrec1.3,VZG1,edg-2,lpA1,rec.1.3,vzg-1
|
| Uniprot Accession |
P61794,P61793,Q92633,Q28031
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Rap1 signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Gap junction, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Pathways in cancer
|
| Gene Ensembl |
ENSECAG00000016606, ENSMUSG00000038668, ENSG00000198121, ENSBTAG00000009654, ENSCAFG00845013671, ENSMMUG00000006906
|
Pre-made viral vector of EDG2/LPAR1 cDNA Clones/ORF Plasmid
EDG2/LPAR1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1902 | Pre-made Human LPAR1/EDG2/LPA1 siRNA oligo Duplex | 1902 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo116744 | Pre-made Rat Lpar1/Edg2 siRNA oligo Duplex | 116744 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14745 | Pre-made Mouse Lpar1/Edg2/Kdt2 siRNA oligo Duplex | 14745 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709208 | Pre-made Cynomolgus/Rhesus macaque LPAR1 siRNA oligo Duplex | 709208 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092556 | Pre-made Cat/Feline LPAR1 siRNA oligo Duplex | 101092556 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474800 | Pre-made Dog/Canine LPAR1/EDG2 siRNA oligo Duplex | 474800 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281136 | Pre-made Bovines/Cattle LPAR1/EDG2 siRNA oligo Duplex | 281136 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053797 | Pre-made Equine/Horse LPAR1 siRNA oligo Duplex | 100053797 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EDG2/LPAR1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T92640-Ab | Human | Anti-Human EDG2/LPAR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T92640-Ab | Rat | Anti-Rat EDG2/LPAR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T92640-Ab | Mouse | Anti-Mouse EDG2/LPAR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T92640-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EDG2/LPAR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T92640-Ab | Cat/Feline | Anti-Cat/Feline EDG2/LPAR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T92640-Ab | Dog/Canine | Anti-Dog/Canine EDG2/LPAR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T92640-Ab | Bovines/Cattle | Anti-Bovines/Cattle EDG2/LPAR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T92640-Ab | Equine/Horse | Anti-Equine/Horse EDG2/LPAR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
EDG2/LPAR1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T92640-Ag | Human | Human EDG2/LPAR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T92640-Ag | Rat | Rat EDG2/LPAR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T92640-Ag | Mouse | Mouse EDG2/LPAR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T92640-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EDG2/LPAR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T92640-Ag | Cat/Feline | Cat/Feline EDG2/LPAR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T92640-Ag | Dog/Canine | Dog/Canine EDG2/LPAR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T92640-Ag | Bovines/Cattle | Bovines/Cattle EDG2/LPAR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T92640-Ag | Equine/Horse | Equine/Horse EDG2/LPAR1 VLP (virus-like particle) | HEK293 | Products Developing |
