Explore ADRA1A gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T92609
|
| Target Name |
ADRA1A
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
148
|
| Gene ID |
100054461 (Equus caballus), 101098375 (Felis catus), 11549 (Mus musculus), 148 (Homo sapiens)
282134 (Bos taurus), 29412 (Rattus norvegicus), 403866 (Canis lupus familiaris), 712509 (Macaca mulatta)
|
| Target Alternative Names |
ADRA1A,ADRA1C,ADRA1L1,ALPHA-1A,ALPHA1AAR,Adra1a,Adra1c,Alpha-1A adrenergic receptor,Alpha-1A adrenoreceptor (Alpha-1A adrenoceptor),Alpha-1C adrenergic receptor,Alpha-adrenergic receptor 1c
|
| Uniprot Accession |
P97718,P35348,P18130,P43140,O77621
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion
|
| Gene Ensembl |
ENSECAG00000015917, ENSMUSG00000045875, ENSG00000120907, ENSBTAG00000031632, ENSCAFG00845012931, ENSMMUG00000023112
|
| Target Classification |
GPCR
|
Pre-made viral vector of ADRA1A cDNA Clones/ORF Plasmid
ADRA1A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo148 | Pre-made Human ADRA1A/ADRA1C/ADRA1L1 siRNA oligo Duplex | 148 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29412 | Pre-made Rat Adra1a/Adra1c siRNA oligo Duplex | 29412 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11549 | Pre-made Mouse Adra1a/Adra1c siRNA oligo Duplex | 11549 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712509 | Pre-made Cynomolgus/Rhesus macaque ADRA1A siRNA oligo Duplex | 712509 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098375 | Pre-made Cat/Feline ADRA1A siRNA oligo Duplex | 101098375 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403866 | Pre-made Dog/Canine ADRA1A/ADRA1C/ALPHA-1A siRNA oligo Duplex | 403866 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282134 | Pre-made Bovines/Cattle ADRA1A siRNA oligo Duplex | 282134 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054461 | Pre-made Equine/Horse ADRA1A siRNA oligo Duplex | 100054461 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ADRA1A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T92609-Ab | Human | Anti-Human ADRA1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T92609-Ab | Rat | Anti-Rat ADRA1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T92609-Ab | Mouse | Anti-Mouse ADRA1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T92609-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ADRA1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T92609-Ab | Cat/Feline | Anti-Cat/Feline ADRA1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T92609-Ab | Dog/Canine | Anti-Dog/Canine ADRA1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T92609-Ab | Bovines/Cattle | Anti-Bovines/Cattle ADRA1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T92609-Ab | Equine/Horse | Anti-Equine/Horse ADRA1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ADRA1A VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T92609-Ag | Human | Human ADRA1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T92609-Ag | Rat | Rat ADRA1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T92609-Ag | Mouse | Mouse ADRA1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T92609-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ADRA1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T92609-Ag | Cat/Feline | Cat/Feline ADRA1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T92609-Ag | Dog/Canine | Dog/Canine ADRA1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T92609-Ag | Bovines/Cattle | Bovines/Cattle ADRA1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T92609-Ag | Equine/Horse | Equine/Horse ADRA1A VLP (virus-like particle) | HEK293 | Products Developing |
