Explore CAPN1/Calpain 1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
| Target ID |
GM-T92517
|
| Target Name |
CAPN1/Calpain 1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
823
|
| Gene ID |
100051106 (Equus caballus), 101096916 (Felis catus), 12333 (Mus musculus), 281661 (Bos taurus) 29153 (Rattus norvegicus), 483745 (Canis lupus familiaris), 716618 (Macaca mulatta), 823 (Homo sapiens)
|
| Target Alternative Names |
CANP,CANP 1,CANP1,CANPL1,CAPN1,Calcium-activated neutral proteinase 1 (CANP 1),Calpain 1,Calpain mu-type,Calpain-1 catalytic subunit,Calpain-1 large subunit,Capa-1,Capa1,Capn1,Cell proliferation-inducing gene 30 protein,Micromolar-calpain (muCANP),SPG76,mu-calpin,muCANP,muCL
|
| Uniprot Accession |
O35350,Q27970,P97571,P07384
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
Lung Cancer
|
| Disease from KEGG |
Protein processing in endoplasmic reticulum, Apoptosis, Cellular senescence, Alzheimer disease
|
| Gene Ensembl |
ENSECAG00000022942, ENSMUSG00000024942, ENSBTAG00000010230, ENSCAFG00845025353, ENSMMUG00000013475, ENSG00000014216
|
Pre-made viral vector of CAPN1/Calpain 1 cDNA Clones/ORF Plasmid
CAPN1/Calpain 1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo823 | Pre-made Human CAPN1/CANP/muCL siRNA oligo Duplex | 823 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29153 | Pre-made Rat Capn1/CANP 1/muCANP siRNA oligo Duplex | 29153 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12333 | Pre-made Mouse Capn1/Capa1/Capa-1 siRNA oligo Duplex | 12333 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716618 | Pre-made Cynomolgus/Rhesus macaque CAPN1 siRNA oligo Duplex | 716618 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096916 | Pre-made Cat/Feline CAPN1 siRNA oligo Duplex | 101096916 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483745 | Pre-made Dog/Canine CAPN1 siRNA oligo Duplex | 483745 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281661 | Pre-made Bovines/Cattle CAPN1/CANP1/CANP 1 siRNA oligo Duplex | 281661 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051106 | Pre-made Equine/Horse CAPN1 siRNA oligo Duplex | 100051106 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CAPN1/Calpain 1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T92517-Ab | Human | Anti-Human CAPN1/Calpain 1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T92517-Ab | Rat | Anti-Rat CAPN1/Calpain 1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T92517-Ab | Mouse | Anti-Mouse CAPN1/Calpain 1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T92517-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CAPN1/Calpain 1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T92517-Ab | Cat/Feline | Anti-Cat/Feline CAPN1/Calpain 1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T92517-Ab | Dog/Canine | Anti-Dog/Canine CAPN1/Calpain 1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T92517-Ab | Bovines/Cattle | Anti-Bovines/Cattle CAPN1/Calpain 1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T92517-Ab | Equine/Horse | Anti-Equine/Horse CAPN1/Calpain 1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
CAPN1/Calpain 1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T92517-Ag | Human | Human CAPN1/Calpain 1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T92517-Ag | Rat | Rat CAPN1/Calpain 1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T92517-Ag | Mouse | Mouse CAPN1/Calpain 1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T92517-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CAPN1/Calpain 1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T92517-Ag | Cat/Feline | Cat/Feline CAPN1/Calpain 1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T92517-Ag | Dog/Canine | Dog/Canine CAPN1/Calpain 1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T92517-Ag | Bovines/Cattle | Bovines/Cattle CAPN1/Calpain 1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T92517-Ag | Equine/Horse | Equine/Horse CAPN1/Calpain 1 recombinant protein | Mammalian cell | Detail |