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Target
sublocation: Introcelluar Protein.
This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T92494
|
| Target Name |
eEF2K/EEF2K/eEF-2K
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
29904
|
| Gene ID |
100058387 (Equus caballus), 101101433 (Felis catus), 13631 (Mus musculus), 25435 (Rattus norvegicus)
29904 (Homo sapiens), 479812 (Canis lupus familiaris), 521730 (Bos taurus), 698604 (Macaca mulatta)
|
| Target Alternative Names |
CaMKIII,Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase,EEF2K,Eef2k,Eukaryotic elongation factor 2 kinase,HSU93850,SMEF2K,eEF-2 kinase,eEF-2K,eEF2K
|
| Uniprot Accession |
O08796,P70531,O00418
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Oxytocin signaling pathway
|
| Gene Ensembl |
ENSECAG00000022924, ENSMUSG00000035064, ENSG00000103319, ENSCAFG00845002598, ENSBTAG00000017662, ENSMMUG00000017725
|
| Target Classification |
Kinase
|
Pre-made viral vector of eEF2K/EEF2K/eEF-2K cDNA Clones/ORF Plasmid
eEF2K/EEF2K/eEF-2K siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo29904 | Pre-made Human EEF2K/eEF-2K/CaMKIII siRNA oligo Duplex | 29904 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25435 | Pre-made Rat Eef2k/SMEF2K siRNA oligo Duplex | 25435 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13631 | Pre-made Mouse Eef2k/eEF-2K siRNA oligo Duplex | 13631 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698604 | Pre-made Cynomolgus/Rhesus macaque EEF2K siRNA oligo Duplex | 698604 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101433 | Pre-made Cat/Feline EEF2K siRNA oligo Duplex | 101101433 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479812 | Pre-made Dog/Canine EEF2K siRNA oligo Duplex | 479812 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo521730 | Pre-made Bovines/Cattle EEF2K siRNA oligo Duplex | 521730 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058387 | Pre-made Equine/Horse EEF2K siRNA oligo Duplex | 100058387 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
eEF2K/EEF2K/eEF-2K antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T92494-Ab | Human | Anti-Human eEF2K/EEF2K/eEF-2K monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T92494-Ab | Rat | Anti-Rat eEF2K/EEF2K/eEF-2K monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T92494-Ab | Mouse | Anti-Mouse eEF2K/EEF2K/eEF-2K monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T92494-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque eEF2K/EEF2K/eEF-2K monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T92494-Ab | Cat/Feline | Anti-Cat/Feline eEF2K/EEF2K/eEF-2K monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T92494-Ab | Dog/Canine | Anti-Dog/Canine eEF2K/EEF2K/eEF-2K monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T92494-Ab | Bovines/Cattle | Anti-Bovines/Cattle eEF2K/EEF2K/eEF-2K monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T92494-Ab | Equine/Horse | Anti-Equine/Horse eEF2K/EEF2K/eEF-2K monoclonal antibody | mab | Therapeutics Target antibody | Detail |
eEF2K/EEF2K/eEF-2K recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T92494-Ag | Human | Human eEF2K/EEF2K/eEF-2K recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T92494-Ag | Rat | Rat eEF2K/EEF2K/eEF-2K recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T92494-Ag | Mouse | Mouse eEF2K/EEF2K/eEF-2K recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T92494-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque eEF2K/EEF2K/eEF-2K recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T92494-Ag | Cat/Feline | Cat/Feline eEF2K/EEF2K/eEF-2K recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T92494-Ag | Dog/Canine | Dog/Canine eEF2K/EEF2K/eEF-2K recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T92494-Ag | Bovines/Cattle | Bovines/Cattle eEF2K/EEF2K/eEF-2K recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T92494-Ag | Equine/Horse | Equine/Horse eEF2K/EEF2K/eEF-2K recombinant protein | Mammalian cell | Detail |
