Explore RYR1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a ryanodine receptor found in skeletal muscle. The encoded protein functions as a calcium release channel in the sarcoplasmic reticulum but also serves to connect the sarcoplasmic reticulum and transverse tubule. Mutations in this gene are associated with malignant hyperthermia susceptibility, central core disease, and minicore myopathy with external ophthalmoplegia. Alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T92328
|
| Target Name |
RYR1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6261
|
| Gene ID |
100034090 (Equus caballus), 100139857 (Bos taurus), 101094224 (Felis catus), 114207 (Rattus norvegicus)
20190 (Mus musculus), 606491 (Canis lupus familiaris), 6261 (Homo sapiens), 693612 (Macaca mulatta)
|
| Target Alternative Names |
RYR1,Ryr1,RYR-1,Ryr1l,Ryr,skrr,CCO,KDS,MHS,RYR,MHS1,RYDR,SKRR,CMYO1A,CMYO1B,CMYP1A,CMYP1B,PPP1R137
|
| Uniprot Accession |
F1LMY4,E9PZQ0,P21817
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Calcium signaling pathway, Circadian entrainment, Oxytocin signaling pathway
|
| Gene Ensembl |
ENSECAG00000015344, ENSBTAG00000006999, ENSMUSG00000030592, ENSCAFG00845005309, ENSG00000196218, ENSMMUG00000002897
|
| Target Classification |
|
RYR1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6261 | Pre-made Human RYR1/CCO/KDS siRNA oligo Duplex | 6261 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo114207 | Pre-made Rat Ryr1/RYR-1/Ryr1l siRNA oligo Duplex | 114207 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20190 | Pre-made Mouse Ryr1/Ryr/skrr siRNA oligo Duplex | 20190 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693612 | Pre-made Cynomolgus/Rhesus macaque RYR1 siRNA oligo Duplex | 693612 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094224 | Pre-made Cat/Feline RYR1 siRNA oligo Duplex | 101094224 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo606491 | Pre-made Dog/Canine RYR1 siRNA oligo Duplex | 606491 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100139857 | Pre-made Bovines/Cattle RYR1 siRNA oligo Duplex | 100139857 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034090 | Pre-made Equine/Horse RYR1 siRNA oligo Duplex | 100034090 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RYR1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T92328-Ab | Human | Anti-Human RYR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T92328-Ab | Rat | Anti-Rat RYR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T92328-Ab | Mouse | Anti-Mouse RYR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T92328-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RYR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T92328-Ab | Cat/Feline | Anti-Cat/Feline RYR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T92328-Ab | Dog/Canine | Anti-Dog/Canine RYR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T92328-Ab | Bovines/Cattle | Anti-Bovines/Cattle RYR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T92328-Ab | Equine/Horse | Anti-Equine/Horse RYR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
RYR1 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T92328-Ag | Human | Human RYR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T92328-Ag | Rat | Rat RYR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T92328-Ag | Mouse | Mouse RYR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T92328-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RYR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T92328-Ag | Cat/Feline | Cat/Feline RYR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T92328-Ag | Dog/Canine | Dog/Canine RYR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T92328-Ag | Bovines/Cattle | Bovines/Cattle RYR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T92328-Ag | Equine/Horse | Equine/Horse RYR1 VLP (virus-like particle) | HEK293 | Products Developing |
