Explore NPTX2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009]
| Target ID |
GM-T92281
|
| Target Name |
NPTX2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4885
|
| Gene ID |
100062989 (Equus caballus), 100336779 (Bos taurus), 100855792 (Canis lupus familiaris), 101094720 (Felis catus) 288475 (Rattus norvegicus), 4885 (Homo sapiens), 53324 (Mus musculus), 718428 (Macaca mulatta)
|
| Target Alternative Names |
NARP,NP-II,NP2,NPTX2,Narp,Neuronal pentraxin II (NP-II),Neuronal pentraxin-2,Nptx2,np2
|
| Uniprot Accession |
P97738,P47972,O70340
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSECAG00000012370, ENSBTAG00000045896, ENSCAFG00845004136, ENSG00000106236, ENSMUSG00000059991, ENSMMUG00000011970
|
Pre-made viral vector of NPTX2 cDNA Clones/ORF Plasmid
NPTX2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4885 | Pre-made Human NPTX2/NP2/NARP siRNA oligo Duplex | 4885 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo288475 | Pre-made Rat Nptx2/NP2/Narp siRNA oligo Duplex | 288475 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo53324 | Pre-made Mouse Nptx2/np2/Narp siRNA oligo Duplex | 53324 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718428 | Pre-made Cynomolgus/Rhesus macaque NPTX2 siRNA oligo Duplex | 718428 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094720 | Pre-made Cat/Feline NPTX2 siRNA oligo Duplex | 101094720 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100855792 | Pre-made Dog/Canine NPTX2 siRNA oligo Duplex | 100855792 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100336779 | Pre-made Bovines/Cattle NPTX2 siRNA oligo Duplex | 100336779 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100062989 | Pre-made Equine/Horse NPTX2 siRNA oligo Duplex | 100062989 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NPTX2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T92281-Ab | Human | Anti-Human NPTX2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T92281-Ab | Rat | Anti-Rat NPTX2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T92281-Ab | Mouse | Anti-Mouse NPTX2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T92281-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NPTX2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T92281-Ab | Cat/Feline | Anti-Cat/Feline NPTX2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T92281-Ab | Dog/Canine | Anti-Dog/Canine NPTX2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T92281-Ab | Bovines/Cattle | Anti-Bovines/Cattle NPTX2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T92281-Ab | Equine/Horse | Anti-Equine/Horse NPTX2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
NPTX2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T92281-Ag | Human | Human NPTX2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T92281-Ag | Rat | Rat NPTX2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T92281-Ag | Mouse | Mouse NPTX2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T92281-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NPTX2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T92281-Ag | Cat/Feline | Cat/Feline NPTX2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T92281-Ag | Dog/Canine | Dog/Canine NPTX2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T92281-Ag | Bovines/Cattle | Bovines/Cattle NPTX2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T92281-Ag | Equine/Horse | Equine/Horse NPTX2 recombinant protein | Mammalian cell | Detail |