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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008]
| Target ID |
GM-T92189
|
| Target Name |
OGG1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4968
|
| Gene ID |
100058398 (Equus caballus), 101091094 (Felis catus), 18294 (Mus musculus), 484666 (Canis lupus familiaris) 4968 (Homo sapiens), 520497 (Bos taurus), 700481 (Macaca mulatta), 81528 (Rattus norvegicus)
|
| Target Alternative Names |
HMMH,HOGG1,MUTM,Mmh,N-glycosylase/DNA lyase,OGG1,OGH1,Ogg1
|
| Uniprot Accession |
O08760,O15527,O70249
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Lung Cancer
|
| Gene Ensembl |
ENSECAG00000010671, ENSMUSG00000030271, ENSCAFG00845009193, ENSG00000114026, ENSBTAG00000007777, ENSMMUG00000006117
|
Pre-made viral vector of OGG1 cDNA Clones/ORF Plasmid
OGG1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4968 | Pre-made Human OGG1/HMMH/MUTM siRNA oligo Duplex | 4968 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81528 | Pre-made Rat Ogg1 siRNA oligo Duplex | 81528 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18294 | Pre-made Mouse Ogg1/Mmh siRNA oligo Duplex | 18294 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700481 | Pre-made Cynomolgus/Rhesus macaque OGG1 siRNA oligo Duplex | 700481 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091094 | Pre-made Cat/Feline OGG1 siRNA oligo Duplex | 101091094 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484666 | Pre-made Dog/Canine OGG1 siRNA oligo Duplex | 484666 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo520497 | Pre-made Bovines/Cattle OGG1 siRNA oligo Duplex | 520497 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058398 | Pre-made Equine/Horse OGG1 siRNA oligo Duplex | 100058398 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
OGG1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T92189-Ab | Human | Anti-Human OGG1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T92189-Ab | Rat | Anti-Rat OGG1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T92189-Ab | Mouse | Anti-Mouse OGG1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T92189-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque OGG1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T92189-Ab | Cat/Feline | Anti-Cat/Feline OGG1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T92189-Ab | Dog/Canine | Anti-Dog/Canine OGG1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T92189-Ab | Bovines/Cattle | Anti-Bovines/Cattle OGG1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T92189-Ab | Equine/Horse | Anti-Equine/Horse OGG1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
OGG1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T92189-Ag | Human | Human OGG1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T92189-Ag | Rat | Rat OGG1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T92189-Ag | Mouse | Mouse OGG1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T92189-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque OGG1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T92189-Ag | Cat/Feline | Cat/Feline OGG1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T92189-Ag | Dog/Canine | Dog/Canine OGG1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T92189-Ag | Bovines/Cattle | Bovines/Cattle OGG1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T92189-Ag | Equine/Horse | Equine/Horse OGG1 recombinant protein | Mammalian cell | Detail |