Explore CRMP2/DPYSL2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
| Target ID |
GM-T92078
|
| Target Name |
CRMP2/DPYSL2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1808
|
| Gene ID |
100054410 (Equus caballus), 12934 (Mus musculus), 1808 (Homo sapiens), 25416 (Rattus norvegicus)
486107 (Canis lupus familiaris), 533746 (Bos taurus), 554340 (Felis catus), 712368 (Macaca mulatta)
|
| Target Alternative Names |
DPYSL2,Dpysl2,DRP2,Crmp2,Ulip2,TOAD-64,Musunc33,N2A3,CRMP2,DRP-2,ULIP2,CRMP-2,DHPRP2,ULIP-2
|
| Uniprot Accession |
O08553,Q16555,P47942,O02675
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Axon guidance
|
| Gene Ensembl |
ENSECAG00000008662, ENSMUSG00000022048, ENSG00000092964, ENSCAFG00845013099, ENSBTAG00000018373, ENSMMUG00000012718
|
| Target Classification |
|
CRMP2/DPYSL2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1808 | Pre-made Human DPYSL2/DRP2/N2A3 siRNA oligo Duplex | 1808 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25416 | Pre-made Rat Dpysl2/Crmp2/TOAD-64 siRNA oligo Duplex | 25416 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12934 | Pre-made Mouse Dpysl2/DRP2/Crmp2 siRNA oligo Duplex | 12934 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712368 | Pre-made Cynomolgus/Rhesus macaque DPYSL2 siRNA oligo Duplex | 712368 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo554340 | Pre-made Cat/Feline DPYSL2/CRMP2 siRNA oligo Duplex | 554340 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486107 | Pre-made Dog/Canine DPYSL2 siRNA oligo Duplex | 486107 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo533746 | Pre-made Bovines/Cattle DPYSL2/DRP-2/CRMP-2 siRNA oligo Duplex | 533746 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054410 | Pre-made Equine/Horse DPYSL2 siRNA oligo Duplex | 100054410 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CRMP2/DPYSL2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T92078-Ab | Human | Anti-Human CRMP2/DPYSL2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T92078-Ab | Rat | Anti-Rat CRMP2/DPYSL2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T92078-Ab | Mouse | Anti-Mouse CRMP2/DPYSL2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T92078-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CRMP2/DPYSL2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T92078-Ab | Cat/Feline | Anti-Cat/Feline CRMP2/DPYSL2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T92078-Ab | Dog/Canine | Anti-Dog/Canine CRMP2/DPYSL2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T92078-Ab | Bovines/Cattle | Anti-Bovines/Cattle CRMP2/DPYSL2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T92078-Ab | Equine/Horse | Anti-Equine/Horse CRMP2/DPYSL2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CRMP2/DPYSL2 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T92078-Ag | Human | Human CRMP2/DPYSL2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T92078-Ag | Rat | Rat CRMP2/DPYSL2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T92078-Ag | Mouse | Mouse CRMP2/DPYSL2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T92078-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CRMP2/DPYSL2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T92078-Ag | Cat/Feline | Cat/Feline CRMP2/DPYSL2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T92078-Ag | Dog/Canine | Dog/Canine CRMP2/DPYSL2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T92078-Ag | Bovines/Cattle | Bovines/Cattle CRMP2/DPYSL2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T92078-Ag | Equine/Horse | Equine/Horse CRMP2/DPYSL2 VLP (virus-like particle) | HEK293 | Products Developing |
