Explore Calcium Sensing Receptor/CASR gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a plasma membrane G protein-coupled receptor that senses small changes in circulating calcium concentration. The encoded protein couples this information to intracellular signaling pathways that modify parathyroid hormone secretion or renal cation handling, and thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene are a cause of familial hypocalciuric hypercalcemia, neonatal severe hyperparathyroidism, and autosomal dominant hypocalcemia. [provided by RefSeq, Aug 2017]
| Target ID |
GM-T92076
|
| Target Name |
Calcium Sensing Receptor/CASR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
846
|
| Gene ID |
100034084 (Equus caballus), 100302732 (Felis catus), 12374 (Mus musculus), 24247 (Rattus norvegicus)
281038 (Bos taurus), 488007 (Canis lupus familiaris), 714441 (Macaca mulatta), 846 (Homo sapiens)
|
| Target Alternative Names |
BoPCaR1,CAR,CASR,CaR,CaSR,Calcium Sensing Receptor,Casr,EIG8,Extracellular calcium-sensing receptor,FHH,FIH,GPRC2A,Gprc2a,HHC,HHC1,HYPOC1,NSHPT,PCAR1,PCaR1,Parathyroid cell calcium-sensing receptor 1 (PCaR1),RaKCaR,hCasR
|
| Uniprot Accession |
Q9QY96,P48442,P35384,P41180
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
NOD-like receptor signaling pathway, Parathyroid hormone synthesis, secretion and action
|
| Gene Ensembl |
ENSECAG00000024712, ENSMUSG00000051980, ENSBTAG00000003865, ENSCAFG00845022950, ENSMMUG00000007886, ENSG00000036828
|
| Target Classification |
GPCR, Tumor-associated antigen (TAA)
|
Pre-made viral vector of Calcium Sensing Receptor/CASR cDNA Clones/ORF Plasmid
Calcium Sensing Receptor/CASR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo846 | Pre-made Human CASR/CAR/FHH siRNA oligo Duplex | 846 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24247 | Pre-made Rat Casr/PCaR1/RaKCaR siRNA oligo Duplex | 24247 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12374 | Pre-made Mouse Casr/CaR/Gprc2a siRNA oligo Duplex | 12374 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714441 | Pre-made Cynomolgus/Rhesus macaque CASR siRNA oligo Duplex | 714441 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100302732 | Pre-made Cat/Feline CASR siRNA oligo Duplex | 100302732 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488007 | Pre-made Dog/Canine CASR siRNA oligo Duplex | 488007 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281038 | Pre-made Bovines/Cattle CASR/BoPCaR1 siRNA oligo Duplex | 281038 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034084 | Pre-made Equine/Horse CASR siRNA oligo Duplex | 100034084 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Calcium Sensing Receptor/CASR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T92076-Ab | Human | Anti-Human Calcium Sensing Receptor/CASR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T92076-Ab | Rat | Anti-Rat Calcium Sensing Receptor/CASR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T92076-Ab | Mouse | Anti-Mouse Calcium Sensing Receptor/CASR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T92076-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Calcium Sensing Receptor/CASR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T92076-Ab | Cat/Feline | Anti-Cat/Feline Calcium Sensing Receptor/CASR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T92076-Ab | Dog/Canine | Anti-Dog/Canine Calcium Sensing Receptor/CASR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T92076-Ab | Bovines/Cattle | Anti-Bovines/Cattle Calcium Sensing Receptor/CASR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T92076-Ab | Equine/Horse | Anti-Equine/Horse Calcium Sensing Receptor/CASR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Calcium Sensing Receptor/CASR VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T92076-Ag | Human | Human Calcium Sensing Receptor/CASR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T92076-Ag | Rat | Rat Calcium Sensing Receptor/CASR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T92076-Ag | Mouse | Mouse Calcium Sensing Receptor/CASR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T92076-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Calcium Sensing Receptor/CASR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T92076-Ag | Cat/Feline | Cat/Feline Calcium Sensing Receptor/CASR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T92076-Ag | Dog/Canine | Dog/Canine Calcium Sensing Receptor/CASR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T92076-Ag | Bovines/Cattle | Bovines/Cattle Calcium Sensing Receptor/CASR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T92076-Ag | Equine/Horse | Equine/Horse Calcium Sensing Receptor/CASR VLP (virus-like particle) | HEK293 | Products Developing |
