ERBB4/Erbb-4 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore ERBB4/Erbb-4 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

Pre-made viral vector of ERBB4/Erbb-4 cDNA Clones/ORF Plasmid

ERBB4/Erbb-4 siRNA/miRNA/oligo for RNA interfence (RNAi)

ERBB4/Erbb-4 antibody/GMab

ERBB4/Erbb-4 VLP (virus-like particle)