Explore ROR2 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T91435
|
| Target Name |
ROR2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4920
|
| Gene ID |
100064718 (Equus caballus), 101087689 (Felis catus), 26564 (Mus musculus), 306782 (Rattus norvegicus) 484193 (Canis lupus familiaris), 4920 (Homo sapiens), 715482 (Macaca mulatta), 785924 (Bos taurus)
|
| Target Alternative Names |
BDB,BDB1,NTRKR2,Neurotrophic tyrosine kinase,Ntrkr2,ROR2,Ror2,Tyrosine-protein kinase transmembrane receptor ROR2,receptor-related 2
|
| Uniprot Accession |
Q9Z138,Q01974
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
cancer
|
| Disease from KEGG |
Wnt signaling pathway
|
| Gene Ensembl |
ENSECAG00000022345, ENSMUSG00000021464, ENSCAFG00845017326, ENSG00000169071, ENSMMUG00000020009, ENSBTAG00000005092
|
| Target Classification |
Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
Pre-made viral vector of ROR2 cDNA Clones/ORF Plasmid
ROR2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4920 | Pre-made Human ROR2/BDB/BDB1 siRNA oligo Duplex | 4920 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo306782 | Pre-made Rat Ror2 siRNA oligo Duplex | 306782 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo26564 | Pre-made Mouse Ror2/Ntrkr2 siRNA oligo Duplex | 26564 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo715482 | Pre-made Cynomolgus/Rhesus macaque ROR2 siRNA oligo Duplex | 715482 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087689 | Pre-made Cat/Feline ROR2 siRNA oligo Duplex | 101087689 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484193 | Pre-made Dog/Canine ROR2 siRNA oligo Duplex | 484193 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo785924 | Pre-made Bovines/Cattle ROR2 siRNA oligo Duplex | 785924 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064718 | Pre-made Equine/Horse ROR2 siRNA oligo Duplex | 100064718 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ROR2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T91435-Ab | Human | Anti-Human ROR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T91435-Ab | Rat | Anti-Rat ROR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T91435-Ab | Mouse | Anti-Mouse ROR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T91435-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ROR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T91435-Ab | Cat/Feline | Anti-Cat/Feline ROR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T91435-Ab | Dog/Canine | Anti-Dog/Canine ROR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T91435-Ab | Bovines/Cattle | Anti-Bovines/Cattle ROR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T91435-Ab | Equine/Horse | Anti-Equine/Horse ROR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ROR2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T91435-Ag | Human | Human ROR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T91435-Ag | Rat | Rat ROR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T91435-Ag | Mouse | Mouse ROR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T91435-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ROR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T91435-Ag | Cat/Feline | Cat/Feline ROR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T91435-Ag | Dog/Canine | Dog/Canine ROR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T91435-Ag | Bovines/Cattle | Bovines/Cattle ROR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T91435-Ag | Equine/Horse | Equine/Horse ROR2 VLP (virus-like particle) | HEK293 | Products Developing |