Explore LGR4 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a G-protein coupled receptor that binds R-spondins and activates the Wnt signaling pathway. This Wnt signaling pathway activation is necessary for proper development of many organs of the body. [provided by RefSeq, Oct 2016]
| Target ID |
GM-T90672
|
| Target Name |
LGR4
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
55366
|
| Gene ID |
100072305 (Equus caballus), 101083964 (Felis catus), 107515 (Mus musculus), 286994 (Rattus norvegicus) 476896 (Canis lupus familiaris), 505423 (Bos taurus), 55366 (Homo sapiens), 701736 (Macaca mulatta)
|
| Target Alternative Names |
9130225G07,A330106J01Rik,A930009A08Rik,BNMD17,DPSL,G-protein coupled receptor 48,GPR48,Gpr48,LGR4,Leucine-rich repeat-containing G-protein coupled receptor 4,Lgr4
|
| Uniprot Accession |
A2ARI4,Q9Z2H4,F1MLX5,Q9BXB1
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Wnt signaling pathway
|
| Gene Ensembl |
ENSECAG00000013111, ENSMUSG00000050199, ENSCAFG00845017676, ENSBTAG00000002606, ENSG00000205213, ENSMMUG00000023491
|
| Target Classification |
GPCR
|
Pre-made viral vector of LGR4 cDNA Clones/ORF Plasmid
LGR4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo55366 | Pre-made Human LGR4/DPSL/GPR48 siRNA oligo Duplex | 55366 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo286994 | Pre-made Rat Lgr4/Gpr48 siRNA oligo Duplex | 286994 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo107515 | Pre-made Mouse Lgr4/Gpr48/9130225G07 siRNA oligo Duplex | 107515 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701736 | Pre-made Cynomolgus/Rhesus macaque LGR4 siRNA oligo Duplex | 701736 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083964 | Pre-made Cat/Feline LGR4 siRNA oligo Duplex | 101083964 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476896 | Pre-made Dog/Canine LGR4 siRNA oligo Duplex | 476896 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo505423 | Pre-made Bovines/Cattle LGR4 siRNA oligo Duplex | 505423 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072305 | Pre-made Equine/Horse LGR4 siRNA oligo Duplex | 100072305 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LGR4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T90672-Ab | Human | Anti-Human LGR4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T90672-Ab | Rat | Anti-Rat LGR4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T90672-Ab | Mouse | Anti-Mouse LGR4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T90672-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LGR4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T90672-Ab | Cat/Feline | Anti-Cat/Feline LGR4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T90672-Ab | Dog/Canine | Anti-Dog/Canine LGR4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T90672-Ab | Bovines/Cattle | Anti-Bovines/Cattle LGR4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T90672-Ab | Equine/Horse | Anti-Equine/Horse LGR4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
LGR4 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T90672-Ag | Human | Human LGR4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T90672-Ag | Rat | Rat LGR4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T90672-Ag | Mouse | Mouse LGR4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T90672-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LGR4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T90672-Ag | Cat/Feline | Cat/Feline LGR4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T90672-Ag | Dog/Canine | Dog/Canine LGR4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T90672-Ag | Bovines/Cattle | Bovines/Cattle LGR4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T90672-Ag | Equine/Horse | Equine/Horse LGR4 VLP (virus-like particle) | HEK293 | Products Developing |