Explore PDGF-D/PDGFD gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T90464
|
| Target Name |
PDGF-D/PDGFD
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
80310
|
| Gene ID |
100061488 (Equus caballus), 101084984 (Felis catus), 479460 (Canis lupus familiaris), 525931 (Bos taurus)
66018 (Rattus norvegicus), 704310 (Macaca mulatta), 71785 (Mus musculus), 80310 (Homo sapiens)
|
| Target Alternative Names |
PDGFD,Pdgfd,Scdgfb,rSCDGF-B,1110003I09Rik,IEGF,SCDGFB,MSTP036,SCDGF-B
|
| Uniprot Accession |
Q9EQT1,Q925I7,Q9GZP0
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
EGFR tyrosine kinase inhibitor resistance, MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, Regulation of actin cytoskeleton, Prostate cancer, Melanoma, Choline metabolism in cancer
|
| Gene Ensembl |
ENSECAG00000024746, ENSCAFG00845000627, ENSBTAG00000034827, ENSMMUG00000005353, ENSMUSG00000032006, ENSG00000170962
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of PDGF-D/PDGFD cDNA Clones/ORF Plasmid
PDGF-D/PDGFD siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo80310 | Pre-made Human PDGFD/IEGF/SCDGFB siRNA oligo Duplex | 80310 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo66018 | Pre-made Rat Pdgfd/Scdgfb/rSCDGF-B siRNA oligo Duplex | 66018 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo71785 | Pre-made Mouse Pdgfd/1110003I09Rik siRNA oligo Duplex | 71785 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704310 | Pre-made Cynomolgus/Rhesus macaque PDGFD siRNA oligo Duplex | 704310 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101084984 | Pre-made Cat/Feline PDGFD siRNA oligo Duplex | 101084984 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479460 | Pre-made Dog/Canine PDGFD siRNA oligo Duplex | 479460 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo525931 | Pre-made Bovines/Cattle PDGFD siRNA oligo Duplex | 525931 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100061488 | Pre-made Equine/Horse PDGFD siRNA oligo Duplex | 100061488 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PDGF-D/PDGFD antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T90464-Ab | Human | Anti-Human PDGF-D/PDGFD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T90464-Ab | Rat | Anti-Rat PDGF-D/PDGFD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T90464-Ab | Mouse | Anti-Mouse PDGF-D/PDGFD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T90464-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PDGF-D/PDGFD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T90464-Ab | Cat/Feline | Anti-Cat/Feline PDGF-D/PDGFD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T90464-Ab | Dog/Canine | Anti-Dog/Canine PDGF-D/PDGFD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T90464-Ab | Bovines/Cattle | Anti-Bovines/Cattle PDGF-D/PDGFD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T90464-Ab | Equine/Horse | Anti-Equine/Horse PDGF-D/PDGFD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
PDGF-D/PDGFD recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T90464-Ag | Human | Human PDGF-D/PDGFD recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T90464-Ag | Rat | Rat PDGF-D/PDGFD recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T90464-Ag | Mouse | Mouse PDGF-D/PDGFD recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T90464-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PDGF-D/PDGFD recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T90464-Ag | Cat/Feline | Cat/Feline PDGF-D/PDGFD recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T90464-Ag | Dog/Canine | Dog/Canine PDGF-D/PDGFD recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T90464-Ag | Bovines/Cattle | Bovines/Cattle PDGF-D/PDGFD recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T90464-Ag | Equine/Horse | Equine/Horse PDGF-D/PDGFD recombinant protein | Mammalian cell | Detail |
