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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T90089
|
| Target Name |
SCF/KITLG/MGF
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4254
|
| Gene ID |
100034127 (Equus caballus), 17311 (Mus musculus), 281885 (Bos taurus), 403507 (Canis lupus familiaris)
4254 (Homo sapiens), 493937 (Felis catus), 574254 (Macaca mulatta), 60427 (Rattus norvegicus)
|
| Target Alternative Names |
KITLG,Kitl,Kitlg,MGF,SCF,Gb,SF,Sl,Clo,Con,Mgf,SLF,blz,contrasted,CSF,710-712,DCUA,FPH2,FPHH,KL-1,WS2F,SHEP7,DFNA69
|
| Uniprot Accession |
Q95MD2,P20826,Q28132,Q06220,P21583,P79169,P21581
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, gastrointestinal stromal
|
| Disease from KEGG |
MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer
|
| Gene Ensembl |
ENSECAG00000000152, ENSMUSG00000019966, ENSBTAG00000017549, ENSCAFG00845018506, ENSG00000049130, ENSMMUG00000051340
|
| Target Classification |
|
Pre-made viral vector of SCF/KITLG/MGF cDNA Clones/ORF Plasmid
SCF/KITLG/MGF siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4254 | Pre-made Human KITLG/SF/MGF siRNA oligo Duplex | 4254 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo60427 | Pre-made Rat Kitlg/Mgf/SCF siRNA oligo Duplex | 60427 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17311 | Pre-made Mouse Kitl/Gb/SF siRNA oligo Duplex | 17311 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574254 | Pre-made Cynomolgus/Rhesus macaque KITLG/SCF siRNA oligo Duplex | 574254 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493937 | Pre-made Cat/Feline KITLG/SCF siRNA oligo Duplex | 493937 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403507 | Pre-made Dog/Canine KITLG/CSF/MGF siRNA oligo Duplex | 403507 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281885 | Pre-made Bovines/Cattle KITLG/MGF siRNA oligo Duplex | 281885 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034127 | Pre-made Equine/Horse KITLG/MGF/SCF siRNA oligo Duplex | 100034127 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SCF/KITLG/MGF antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T90089-Ab | Human | Anti-Human SCF/KITLG/MGF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T90089-Ab | Rat | Anti-Rat SCF/KITLG/MGF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T90089-Ab | Mouse | Anti-Mouse SCF/KITLG/MGF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T90089-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SCF/KITLG/MGF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T90089-Ab | Cat/Feline | Anti-Cat/Feline SCF/KITLG/MGF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T90089-Ab | Dog/Canine | Anti-Dog/Canine SCF/KITLG/MGF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T90089-Ab | Bovines/Cattle | Anti-Bovines/Cattle SCF/KITLG/MGF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T90089-Ab | Equine/Horse | Anti-Equine/Horse SCF/KITLG/MGF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
SCF/KITLG/MGF VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T90089-Ag | Human | Human SCF/KITLG/MGF VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T90089-Ag | Rat | Rat SCF/KITLG/MGF VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T90089-Ag | Mouse | Mouse SCF/KITLG/MGF VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T90089-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SCF/KITLG/MGF VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T90089-Ag | Cat/Feline | Cat/Feline SCF/KITLG/MGF VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T90089-Ag | Dog/Canine | Dog/Canine SCF/KITLG/MGF VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T90089-Ag | Bovines/Cattle | Bovines/Cattle SCF/KITLG/MGF VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T90089-Ag | Equine/Horse | Equine/Horse SCF/KITLG/MGF VLP (virus-like particle) | HEK293 | Products Developing |
