Explore DTL gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
Contributes to ubiquitin-protein transferase activity. Involved in several processes, including protein ubiquitination; regulation of G2/M transition of mitotic cell cycle; and translesion synthesis. Located in centrosome; cytosol; and nuclear lumen. Part of Cul4A-RING E3 ubiquitin ligase complex and Cul4B-RING E3 ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID |
GM-T89521
|
| Target Name |
DTL
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
51514
|
| Gene ID |
100054533 (Equus caballus), 101100689 (Felis catus), 305073 (Rattus norvegicus), 490279 (Canis lupus familiaris)
51514 (Homo sapiens), 539953 (Bos taurus), 711236 (Macaca mulatta), 76843 (Mus musculus)
|
| Target Alternative Names |
2810047L02Rik,5730564G15Rik,CDT2,DCAF2,DDB1- and CUL4-associated factor 2,DTL,Denticleless protein homolog,Dtl,L2DTL,L2dtl,Lethal(2) denticleless protein homolog,RAMP,RGD1310439,Ramp,Retinoic acid-regulated nuclear matrix-associated protein
|
| Uniprot Accession |
Q9NZJ0,Q3TLR7
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
Breast Cancer
|
| Gene Ensembl |
ENSECAG00000011878, ENSCAFG00845003601, ENSG00000143476, ENSBTAG00000018142, ENSMMUG00000010176, ENSMUSG00000037474
|
Pre-made viral vector of DTL cDNA Clones/ORF Plasmid
DTL siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo51514 | Pre-made Human DTL/CDT2/RAMP siRNA oligo Duplex | 51514 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo305073 | Pre-made Rat Dtl/RGD1310439 siRNA oligo Duplex | 305073 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo76843 | Pre-made Mouse Dtl/Ramp/L2dtl siRNA oligo Duplex | 76843 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711236 | Pre-made Cynomolgus/Rhesus macaque DTL siRNA oligo Duplex | 711236 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100689 | Pre-made Cat/Feline DTL siRNA oligo Duplex | 101100689 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490279 | Pre-made Dog/Canine DTL siRNA oligo Duplex | 490279 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539953 | Pre-made Bovines/Cattle DTL siRNA oligo Duplex | 539953 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054533 | Pre-made Equine/Horse DTL siRNA oligo Duplex | 100054533 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DTL antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T89521-Ab | Human | Anti-Human DTL monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T89521-Ab | Rat | Anti-Rat DTL monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T89521-Ab | Mouse | Anti-Mouse DTL monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T89521-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DTL monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T89521-Ab | Cat/Feline | Anti-Cat/Feline DTL monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T89521-Ab | Dog/Canine | Anti-Dog/Canine DTL monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T89521-Ab | Bovines/Cattle | Anti-Bovines/Cattle DTL monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T89521-Ab | Equine/Horse | Anti-Equine/Horse DTL monoclonal antibody | mab | Therapeutics Target antibody | Detail |
DTL recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T89521-Ag | Human | Human DTL recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T89521-Ag | Rat | Rat DTL recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T89521-Ag | Mouse | Mouse DTL recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T89521-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DTL recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T89521-Ag | Cat/Feline | Cat/Feline DTL recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T89521-Ag | Dog/Canine | Dog/Canine DTL recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T89521-Ag | Bovines/Cattle | Bovines/Cattle DTL recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T89521-Ag | Equine/Horse | Equine/Horse DTL recombinant protein | Mammalian cell | Detail |
