Explore IMPDH2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T89360
|
| Target Name |
IMPDH2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3615
|
| Gene ID |
100063255 (Equus caballus), 101080693 (Felis catus), 23918 (Mus musculus), 301005 (Rattus norvegicus)
3615 (Homo sapiens), 476630 (Canis lupus familiaris), 511969 (Bos taurus), 708307 (Macaca mulatta)
|
| Target Alternative Names |
IMP dehydrogenase 2,IMPD,IMPD 2,IMPD2,IMPDH 2,IMPDH-II,IMPDH-II),IMPDH2,Impdh2,Inosine-5'-monophosphate dehydrogenase 2,Inosine-5'-monophosphate dehydrogenase type II (IMP dehydrogenase II
|
| Uniprot Accession |
P24547,E9PU28,P12268,Q3SWY3
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
Lung Cancer
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000006885, ENSMUSG00000062867, ENSG00000178035, ENSCAFG00845029196, ENSBTAG00000031837, ENSMMUG00000005656
|
Pre-made viral vector of IMPDH2 cDNA Clones/ORF Plasmid
IMPDH2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3615 | Pre-made Human IMPDH2/IMPD2/IMPDH-II siRNA oligo Duplex | 3615 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo301005 | Pre-made Rat Impdh2/IMPD 2/IMPDH 2 siRNA oligo Duplex | 301005 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo23918 | Pre-made Mouse Impdh2/IMPD/IMPD 2 siRNA oligo Duplex | 23918 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708307 | Pre-made Cynomolgus/Rhesus macaque IMPDH2 siRNA oligo Duplex | 708307 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080693 | Pre-made Cat/Feline IMPDH2 siRNA oligo Duplex | 101080693 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476630 | Pre-made Dog/Canine IMPDH2 siRNA oligo Duplex | 476630 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo511969 | Pre-made Bovines/Cattle IMPDH2 siRNA oligo Duplex | 511969 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100063255 | Pre-made Equine/Horse IMPDH2 siRNA oligo Duplex | 100063255 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IMPDH2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T89360-Ab | Human | Anti-Human IMPDH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T89360-Ab | Rat | Anti-Rat IMPDH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T89360-Ab | Mouse | Anti-Mouse IMPDH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T89360-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IMPDH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T89360-Ab | Cat/Feline | Anti-Cat/Feline IMPDH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T89360-Ab | Dog/Canine | Anti-Dog/Canine IMPDH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T89360-Ab | Bovines/Cattle | Anti-Bovines/Cattle IMPDH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T89360-Ab | Equine/Horse | Anti-Equine/Horse IMPDH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
IMPDH2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T89360-Ag | Human | Human IMPDH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T89360-Ag | Rat | Rat IMPDH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T89360-Ag | Mouse | Mouse IMPDH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T89360-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IMPDH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T89360-Ag | Cat/Feline | Cat/Feline IMPDH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T89360-Ag | Dog/Canine | Dog/Canine IMPDH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T89360-Ag | Bovines/Cattle | Bovines/Cattle IMPDH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T89360-Ag | Equine/Horse | Equine/Horse IMPDH2 recombinant protein | Mammalian cell | Detail |
