Explore NPY1R gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity. [provided by RefSeq, Aug 2013]
| Target ID |
GM-T89213
|
| Target Name |
NPY1R
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4886
|
| Gene ID |
100061686 (Equus caballus), 101099875 (Felis catus), 18166 (Mus musculus), 29358 (Rattus norvegicus) 399518 (Canis lupus familiaris), 4886 (Homo sapiens), 504813 (Bos taurus), 574206 (Macaca mulatta)
|
| Target Alternative Names |
NPY-1,NPY1-R,NPY1R,NPYR,Neuropeptide Y receptor type 1,Npy1r,Npyr,Y1-R
|
| Uniprot Accession |
Q04573,P21555,O02813,P25929,Q1RMU8
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
cAMP signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes
|
| Gene Ensembl |
ENSECAG00000016717, ENSMUSG00000036437, ENSCAFG00845006432, ENSG00000164128, ENSBTAG00000047586, ENSMMUG00000060090
|
| Target Classification |
GPCR
|
Pre-made viral vector of NPY1R cDNA Clones/ORF Plasmid
NPY1R siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4886 | Pre-made Human NPY1R/NPYR/NPY1-R siRNA oligo Duplex | 4886 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29358 | Pre-made Rat Npy1r/NPY-1 siRNA oligo Duplex | 29358 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18166 | Pre-made Mouse Npy1r/Npyr/Y1-R siRNA oligo Duplex | 18166 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574206 | Pre-made Cynomolgus/Rhesus macaque NPY1R siRNA oligo Duplex | 574206 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099875 | Pre-made Cat/Feline NPY1R siRNA oligo Duplex | 101099875 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo399518 | Pre-made Dog/Canine NPY1R siRNA oligo Duplex | 399518 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo504813 | Pre-made Bovines/Cattle NPY1R siRNA oligo Duplex | 504813 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100061686 | Pre-made Equine/Horse NPY1R siRNA oligo Duplex | 100061686 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NPY1R antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T89213-Ab | Human | Anti-Human NPY1R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T89213-Ab | Rat | Anti-Rat NPY1R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T89213-Ab | Mouse | Anti-Mouse NPY1R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T89213-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NPY1R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T89213-Ab | Cat/Feline | Anti-Cat/Feline NPY1R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T89213-Ab | Dog/Canine | Anti-Dog/Canine NPY1R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T89213-Ab | Bovines/Cattle | Anti-Bovines/Cattle NPY1R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T89213-Ab | Equine/Horse | Anti-Equine/Horse NPY1R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
NPY1R VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T89213-Ag | Human | Human NPY1R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T89213-Ag | Rat | Rat NPY1R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T89213-Ag | Mouse | Mouse NPY1R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T89213-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NPY1R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T89213-Ag | Cat/Feline | Cat/Feline NPY1R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T89213-Ag | Dog/Canine | Dog/Canine NPY1R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T89213-Ag | Bovines/Cattle | Bovines/Cattle NPY1R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T89213-Ag | Equine/Horse | Equine/Horse NPY1R VLP (virus-like particle) | HEK293 | Products Developing |