Explore Connexin-26/GJB2/Cx26 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness. [provided by RefSeq, Oct 2008]
Target ID |
GM-T88947
|
Target Name |
Connexin-26/GJB2/Cx26
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
2706
|
Gene ID |
100050084 (Equus caballus), 101082540 (Felis catus), 14619 (Mus musculus), 2706 (Homo sapiens) 394266 (Rattus norvegicus), 403570 (Canis lupus familiaris), 407154 (Bos taurus), 704224 (Macaca mulatta)
|
Target Alternative Names |
GJB2,Gjb2,CXNE,Cx26,Cxne,Cnx26,Gjb-2,HID,KID,PPK,BAPS,CX26,DFNA3,DFNB1,NSRD1,DFNA3A,DFNB1A,CXN-26
|
Uniprot Accession |
Q00977,P29033,P21994,A2VE67,Q8MIT8
|
Uniprot Entry Name |
|
Protein Sub-location |
Transmembrane Protein
|
Category |
Therapeutics Target
|
Disease |
cancer
|
Disease from KEGG |
|
Gene Ensembl |
ENSECAG00000034421, ENSMUSG00000046352, ENSG00000165474, ENSCAFG00845023429, ENSBTAG00000017425, ENSMMUG00000010522
|
Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of Connexin-26/GJB2/Cx26 cDNA Clones/ORF Plasmid
Connexin-26/GJB2/Cx26 siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo2706 | Pre-made Human GJB2/HID/KID siRNA oligo Duplex | 2706 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo394266 | Pre-made Rat Gjb2/Cx26/Cxne siRNA oligo Duplex | 394266 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo14619 | Pre-made Mouse Gjb2/Cx26/Cxne siRNA oligo Duplex | 14619 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo704224 | Pre-made Cynomolgus/Rhesus macaque GJB2/CXNE siRNA oligo Duplex | 704224 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo101082540 | Pre-made Cat/Feline GJB2 siRNA oligo Duplex | 101082540 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo403570 | Pre-made Dog/Canine GJB2/CX26 siRNA oligo Duplex | 403570 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo407154 | Pre-made Bovines/Cattle GJB2/CX26 siRNA oligo Duplex | 407154 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100050084 | Pre-made Equine/Horse GJB2/CXNE siRNA oligo Duplex | 100050084 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Connexin-26/GJB2/Cx26 antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-T88947-Ab | Human | Anti-Human Connexin-26/GJB2/Cx26 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-rg-T88947-Ab | Rat | Anti-Rat Connexin-26/GJB2/Cx26 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-mg-T88947-Ab | Mouse | Anti-Mouse Connexin-26/GJB2/Cx26 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-cynog-T88947-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Connexin-26/GJB2/Cx26 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-felg-T88947-Ab | Cat/Feline | Anti-Cat/Feline Connexin-26/GJB2/Cx26 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-cang-T88947-Ab | Dog/Canine | Anti-Dog/Canine Connexin-26/GJB2/Cx26 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-bovg-T88947-Ab | Bovines/Cattle | Anti-Bovines/Cattle Connexin-26/GJB2/Cx26 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-equg-T88947-Ab | Equine/Horse | Anti-Equine/Horse Connexin-26/GJB2/Cx26 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Connexin-26/GJB2/Cx26 VLP (virus-like particle)
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-T88947-Ag | Human | Human Connexin-26/GJB2/Cx26 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-rg-T88947-Ag | Rat | Rat Connexin-26/GJB2/Cx26 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-mg-T88947-Ag | Mouse | Mouse Connexin-26/GJB2/Cx26 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-cynog-T88947-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Connexin-26/GJB2/Cx26 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-felg-T88947-Ag | Cat/Feline | Cat/Feline Connexin-26/GJB2/Cx26 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-cang-T88947-Ag | Dog/Canine | Dog/Canine Connexin-26/GJB2/Cx26 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-bovg-T88947-Ag | Bovines/Cattle | Bovines/Cattle Connexin-26/GJB2/Cx26 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-equg-T88947-Ag | Equine/Horse | Equine/Horse Connexin-26/GJB2/Cx26 VLP (virus-like particle) | HEK293 | Products Developing |