Explore MYCN gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
| Target ID |
GM-T88786
|
| Target Name |
MYCN
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4613
|
| Gene ID |
100146296 (Equus caballus), 101093013 (Felis catus), 18109 (Mus musculus), 298894 (Rattus norvegicus)
4613 (Homo sapiens), 482978 (Canis lupus familiaris), 616888 (Bos taurus), 698699 (Macaca mulatta)
|
| Target Alternative Names |
Class E basic helix-loop-helix protein 37 (bHLHe37),FGLDS1,MODED,MPAPA,MYCN,MYCNsORF,MYCNsPEP,Mycn,N-MYC1,N-myc,N-myc proto-oncogene protein,NMYC,Nmuc1,Nmyc,Nmyc-1,Nmyc1,ODED,bHLHe37,c-nmyc
|
| Uniprot Accession |
P03966,Q63379,P04198
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000002896, ENSMUSG00000037169, ENSG00000134323, ENSCAFG00845016124, ENSBTAG00000023372, ENSMMUG00000052363
|
| Target Classification |
Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
Pre-made viral vector of MYCN cDNA Clones/ORF Plasmid
MYCN siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4613 | Pre-made Human MYCN/NMYC/ODED siRNA oligo Duplex | 4613 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo298894 | Pre-made Rat Mycn/Nmyc/N-myc siRNA oligo Duplex | 298894 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18109 | Pre-made Mouse Mycn/Nmyc/N-myc siRNA oligo Duplex | 18109 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698699 | Pre-made Cynomolgus/Rhesus macaque MYCN siRNA oligo Duplex | 698699 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093013 | Pre-made Cat/Feline MYCN siRNA oligo Duplex | 101093013 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482978 | Pre-made Dog/Canine MYCN/N-MYC1 siRNA oligo Duplex | 482978 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo616888 | Pre-made Bovines/Cattle MYCN siRNA oligo Duplex | 616888 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100146296 | Pre-made Equine/Horse MYCN siRNA oligo Duplex | 100146296 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MYCN antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T88786-Ab | Human | Anti-Human MYCN monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T88786-Ab | Rat | Anti-Rat MYCN monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T88786-Ab | Mouse | Anti-Mouse MYCN monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T88786-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MYCN monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T88786-Ab | Cat/Feline | Anti-Cat/Feline MYCN monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T88786-Ab | Dog/Canine | Anti-Dog/Canine MYCN monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T88786-Ab | Bovines/Cattle | Anti-Bovines/Cattle MYCN monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T88786-Ab | Equine/Horse | Anti-Equine/Horse MYCN monoclonal antibody | mab | Therapeutics Target antibody | Detail |
MYCN recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T88786-Ag | Human | Human MYCN recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T88786-Ag | Rat | Rat MYCN recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T88786-Ag | Mouse | Mouse MYCN recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T88786-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MYCN recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T88786-Ag | Cat/Feline | Cat/Feline MYCN recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T88786-Ag | Dog/Canine | Dog/Canine MYCN recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T88786-Ag | Bovines/Cattle | Bovines/Cattle MYCN recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T88786-Ag | Equine/Horse | Equine/Horse MYCN recombinant protein | Mammalian cell | Detail |
