Explore LMO2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Nov 2008]
| Target ID |
GM-T88321
|
| Target Name |
LMO2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4005
|
| Gene ID |
100060270 (Equus caballus), 101092888 (Felis catus), 119864212 (Canis lupus familiaris), 16909 (Mus musculus)
362176 (Rattus norvegicus), 4005 (Homo sapiens), 614876 (Bos taurus), 717502 (Macaca mulatta)
|
| Target Alternative Names |
Cysteine-rich protein TTG-2,LIM domain only protein 2 (LMO-2),LMO-2,LMO2,Lmo2,RBTN2,RBTNL1,RHOM2,Rbtn-2,Rbtn2,Rhom-2,Rhombotin-2,T-cell translocation protein 2,TTG2,Ttg2
|
| Uniprot Accession |
P25801,P25791,Q1LZ94
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000007061, ENSMUSG00000032698, ENSG00000135363, ENSBTAG00000006951, ENSMMUG00000007633
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of LMO2 cDNA Clones/ORF Plasmid
LMO2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4005 | Pre-made Human LMO2/TTG2/LMO-2 siRNA oligo Duplex | 4005 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362176 | Pre-made Rat Lmo2 siRNA oligo Duplex | 362176 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16909 | Pre-made Mouse Lmo2/Ttg2/Rbtn2 siRNA oligo Duplex | 16909 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717502 | Pre-made Cynomolgus/Rhesus macaque LMO2 siRNA oligo Duplex | 717502 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092888 | Pre-made Cat/Feline LMO2 siRNA oligo Duplex | 101092888 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo119864212 | Pre-made Dog/Canine LMO2 siRNA oligo Duplex | 119864212 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo614876 | Pre-made Bovines/Cattle LMO2 siRNA oligo Duplex | 614876 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060270 | Pre-made Equine/Horse LMO2 siRNA oligo Duplex | 100060270 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LMO2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T88321-Ab | Human | Anti-Human LMO2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T88321-Ab | Rat | Anti-Rat LMO2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T88321-Ab | Mouse | Anti-Mouse LMO2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T88321-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LMO2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T88321-Ab | Cat/Feline | Anti-Cat/Feline LMO2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T88321-Ab | Dog/Canine | Anti-Dog/Canine LMO2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T88321-Ab | Bovines/Cattle | Anti-Bovines/Cattle LMO2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T88321-Ab | Equine/Horse | Anti-Equine/Horse LMO2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
LMO2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T88321-Ag | Human | Human LMO2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T88321-Ag | Rat | Rat LMO2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T88321-Ag | Mouse | Mouse LMO2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T88321-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LMO2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T88321-Ag | Cat/Feline | Cat/Feline LMO2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T88321-Ag | Dog/Canine | Dog/Canine LMO2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T88321-Ag | Bovines/Cattle | Bovines/Cattle LMO2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T88321-Ag | Equine/Horse | Equine/Horse LMO2 recombinant protein | Mammalian cell | Detail |
