Explore TNFRSF8/CD30 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T88023
|
| Target Name |
TNFRSF8/CD30
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
943
|
| Gene ID |
100055885 (Equus caballus), 101101575 (Felis catus), 21941 (Mus musculus), 25069 (Rattus norvegicus)
487438 (Canis lupus familiaris), 614780 (Bos taurus), 722773 (Macaca mulatta), 943 (Homo sapiens)
|
| Target Alternative Names |
TNFRSF8,Tnfrsf8,Ki,Cd30,Ki-1,D1S166E,CD30
|
| Uniprot Accession |
Q60846,P97525,P28908
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction
|
| Gene Ensembl |
ENSECAG00000014108, ENSMUSG00000028602, ENSCAFG00845001629, ENSBTAG00000039937, ENSMMUG00000008340, ENSG00000120949
|
| Target Classification |
Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
TNFRSF8/CD30 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo943 | Pre-made Human TNFRSF8/CD30/Ki-1 siRNA oligo Duplex | 943 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25069 | Pre-made Rat Tnfrsf8/Cd30 siRNA oligo Duplex | 25069 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21941 | Pre-made Mouse Tnfrsf8/Ki/Cd30 siRNA oligo Duplex | 21941 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo722773 | Pre-made Cynomolgus/Rhesus macaque TNFRSF8 siRNA oligo Duplex | 722773 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101575 | Pre-made Cat/Feline TNFRSF8 siRNA oligo Duplex | 101101575 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487438 | Pre-made Dog/Canine TNFRSF8 siRNA oligo Duplex | 487438 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo614780 | Pre-made Bovines/Cattle TNFRSF8 siRNA oligo Duplex | 614780 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055885 | Pre-made Equine/Horse TNFRSF8 siRNA oligo Duplex | 100055885 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TNFRSF8/CD30 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T88023-Ab | Human | Anti-Human TNFRSF8/CD30 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T88023-Ab | Rat | Anti-Rat TNFRSF8/CD30 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T88023-Ab | Mouse | Anti-Mouse TNFRSF8/CD30 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T88023-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TNFRSF8/CD30 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T88023-Ab | Cat/Feline | Anti-Cat/Feline TNFRSF8/CD30 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T88023-Ab | Dog/Canine | Anti-Dog/Canine TNFRSF8/CD30 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T88023-Ab | Bovines/Cattle | Anti-Bovines/Cattle TNFRSF8/CD30 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T88023-Ab | Equine/Horse | Anti-Equine/Horse TNFRSF8/CD30 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
TNFRSF8/CD30 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T88023-Ag | Human | Human TNFRSF8/CD30 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T88023-Ag | Rat | Rat TNFRSF8/CD30 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T88023-Ag | Mouse | Mouse TNFRSF8/CD30 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T88023-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TNFRSF8/CD30 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T88023-Ag | Cat/Feline | Cat/Feline TNFRSF8/CD30 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T88023-Ag | Dog/Canine | Dog/Canine TNFRSF8/CD30 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T88023-Ag | Bovines/Cattle | Bovines/Cattle TNFRSF8/CD30 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T88023-Ag | Equine/Horse | Equine/Horse TNFRSF8/CD30 VLP (virus-like particle) | HEK293 | Products Developing |
