Explore ROR1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012]
| Target ID |
GM-T87871
|
| Target Name |
ROR1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4919
|
| Gene ID |
100069962 (Equus caballus), 101100987 (Felis catus), 26563 (Mus musculus), 362550 (Rattus norvegicus)
489557 (Canis lupus familiaris), 4919 (Homo sapiens), 700760 (Macaca mulatta), 783965 (Bos taurus)
|
| Target Alternative Names |
2810404D04Rik,Inactive tyrosine-protein kinase transmembrane receptor ROR1,NTRKR1,Neurotrophic tyrosine kinase,Ntrkr1,RGD1559469,ROR1,Ror1,dJ537F10.1,receptor-related 1
|
| Uniprot Accession |
Q9Z139,Q01973
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Disease |
cancer
|
| Disease from KEGG |
Wnt signaling pathway
|
| Gene Ensembl |
ENSECAG00000024107, ENSMUSG00000035305, ENSCAFG00845004850, ENSG00000185483, ENSMMUG00000004668, ENSBTAG00000012312
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of ROR1 cDNA Clones/ORF Plasmid
ROR1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4919 | Pre-made Human ROR1/NTRKR1/dJ537F10.1 siRNA oligo Duplex | 4919 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362550 | Pre-made Rat Ror1/RGD1559469 siRNA oligo Duplex | 362550 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo26563 | Pre-made Mouse Ror1/Ntrkr1/2810404D04Rik siRNA oligo Duplex | 26563 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700760 | Pre-made Cynomolgus/Rhesus macaque ROR1 siRNA oligo Duplex | 700760 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100987 | Pre-made Cat/Feline ROR1 siRNA oligo Duplex | 101100987 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489557 | Pre-made Dog/Canine ROR1 siRNA oligo Duplex | 489557 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo783965 | Pre-made Bovines/Cattle ROR1 siRNA oligo Duplex | 783965 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100069962 | Pre-made Equine/Horse ROR1 siRNA oligo Duplex | 100069962 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ROR1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T87871-Ab | Human | Anti-Human ROR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T87871-Ab | Rat | Anti-Rat ROR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T87871-Ab | Mouse | Anti-Mouse ROR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T87871-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ROR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T87871-Ab | Cat/Feline | Anti-Cat/Feline ROR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T87871-Ab | Dog/Canine | Anti-Dog/Canine ROR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T87871-Ab | Bovines/Cattle | Anti-Bovines/Cattle ROR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T87871-Ab | Equine/Horse | Anti-Equine/Horse ROR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ROR1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T87871-Ag | Human | Human ROR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T87871-Ag | Rat | Rat ROR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T87871-Ag | Mouse | Mouse ROR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T87871-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ROR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T87871-Ag | Cat/Feline | Cat/Feline ROR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T87871-Ag | Dog/Canine | Dog/Canine ROR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T87871-Ag | Bovines/Cattle | Bovines/Cattle ROR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T87871-Ag | Equine/Horse | Equine/Horse ROR1 VLP (virus-like particle) | HEK293 | Products Developing |
