Explore CLEC6A gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a type II membrane receptor with an extracellular C-type lectin-like domain fold. The extracellular portion binds structures with a high mannose content and has been shown to recognize several pathogens, including C. elegans, S. cerevisiae, M. tuberculosis, C. neoformans, and house dust mite. When stimulated, the encoded protein initiates signalling through the CARD9-Bcl10-Malt1 pathway, leading to the induction of cytokines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
| Target ID |
GM-T87719
|
| Target Name |
CLEC6A
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
93978
|
| Gene ID |
105260732 (Felis catus), 514979 (Bos taurus), 716162 (Macaca mulatta), 93978 (Homo sapiens)
|
| Target Alternative Names |
CLEC6A,CLEC4N,CLECSF10,dectin-2,hDECTIN-2
|
| Uniprot Accession |
Q3LUH2,Q6EIG7
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
C-type lectin receptor signaling pathway
|
| Gene Ensembl |
ENSBTAG00000023635, ENSMMUG00000013698, ENSG00000205846
|
| Target Classification |
|
CLEC6A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo93978 | Pre-made Human CLEC6A/CLEC4N/CLECSF10 siRNA oligo Duplex | 93978 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716162 | Pre-made Cynomolgus/Rhesus macaque CLEC6A siRNA oligo Duplex | 716162 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo105260732 | Pre-made Cat/Feline CLEC6A siRNA oligo Duplex | 105260732 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo514979 | Pre-made Bovines/Cattle CLEC6A siRNA oligo Duplex | 514979 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
CLEC6A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T87719-Ab | Human | Anti-Human CLEC6A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T87719-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CLEC6A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T87719-Ab | Cat/Feline | Anti-Cat/Feline CLEC6A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T87719-Ab | Bovines/Cattle | Anti-Bovines/Cattle CLEC6A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CLEC6A VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T87719-Ag | Human | Human CLEC6A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T87719-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CLEC6A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T87719-Ag | Cat/Feline | Cat/Feline CLEC6A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T87719-Ag | Bovines/Cattle | Bovines/Cattle CLEC6A VLP (virus-like particle) | HEK293 | Products Developing |
