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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T87675
|
| Target Name |
AURKA
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6790
|
| Gene ID |
100050161 (Equus caballus), 101091184 (Felis catus), 20878 (Mus musculus), 261730 (Rattus norvegicus) 485940 (Canis lupus familiaris), 504437 (Bos taurus), 6790 (Homo sapiens), 698190 (Macaca mulatta)
|
| Target Alternative Names |
AIK,AIRK1,ARK-1,ARK1,AURA,AURKA,Ark1,Aurka,Aurora 2,Aurora kinase A,Aurora-A,Aurora-related kinase 1),Aurora/IPL1-related kinase 1 (ARK-1,Ayk1,BTAK,Breast tumor-amplified kinase,IAK,IAK1,Ipl1- and aurora-related kinase 1,PPP1R47,STK15,STK6,STK7,Serine/threonine-protein kinase 15,Serine/threonine-protein kinase 6,Serine/threonine-protein kinase Ayk1,Serine/threonine-protein kinase aurora-A,Stk6
|
| Uniprot Accession |
P97477,P59241,Q2TA06,O14965
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000023961, ENSMUSG00000027496, ENSCAFG00845029207, ENSBTAG00000013009, ENSG00000087586, ENSMMUG00000000070
|
| Target Classification |
Kinase, Tumor-associated antigen (TAA)
|
Pre-made viral vector of AURKA cDNA Clones/ORF Plasmid
AURKA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6790 | Pre-made Human AURKA/AIK/ARK1 siRNA oligo Duplex | 6790 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo261730 | Pre-made Rat Aurka/Stk6/ARK-1 siRNA oligo Duplex | 261730 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20878 | Pre-made Mouse Aurka/IAK/Ark1 siRNA oligo Duplex | 20878 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698190 | Pre-made Cynomolgus/Rhesus macaque AURKA siRNA oligo Duplex | 698190 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091184 | Pre-made Cat/Feline AURKA siRNA oligo Duplex | 101091184 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485940 | Pre-made Dog/Canine AURKA siRNA oligo Duplex | 485940 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo504437 | Pre-made Bovines/Cattle AURKA/ARK-1 siRNA oligo Duplex | 504437 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050161 | Pre-made Equine/Horse AURKA siRNA oligo Duplex | 100050161 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
AURKA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T87675-Ab | Human | Anti-Human AURKA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T87675-Ab | Rat | Anti-Rat AURKA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T87675-Ab | Mouse | Anti-Mouse AURKA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T87675-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque AURKA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T87675-Ab | Cat/Feline | Anti-Cat/Feline AURKA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T87675-Ab | Dog/Canine | Anti-Dog/Canine AURKA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T87675-Ab | Bovines/Cattle | Anti-Bovines/Cattle AURKA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T87675-Ab | Equine/Horse | Anti-Equine/Horse AURKA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
AURKA recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T87675-Ag | Human | Human AURKA recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T87675-Ag | Rat | Rat AURKA recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T87675-Ag | Mouse | Mouse AURKA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T87675-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque AURKA recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T87675-Ag | Cat/Feline | Cat/Feline AURKA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T87675-Ag | Dog/Canine | Dog/Canine AURKA recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T87675-Ag | Bovines/Cattle | Bovines/Cattle AURKA recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T87675-Ag | Equine/Horse | Equine/Horse AURKA recombinant protein | Mammalian cell | Detail |