Explore ADORA2B gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T86679
|
| Target Name |
ADORA2B
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
136
|
| Gene ID |
100063319 (Equus caballus), 109494208 (Felis catus), 11541 (Mus musculus), 136 (Homo sapiens)
29316 (Rattus norvegicus), 403410 (Canis lupus familiaris), 529760 (Bos taurus), 696848 (Macaca mulatta)
|
| Target Alternative Names |
A2BAR,A2BR,A2b,AA2BR,ADORA2,ADORA2B,ARA2B,Adenosine receptor A2b,Adora2b
|
| Uniprot Accession |
Q60614,P29275,P29276,Q6W3F4,Q1LZD0
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease from KEGG |
Rap1 signaling pathway, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction
|
| Gene Ensembl |
ENSMUSG00000018500, ENSG00000170425, ENSCAFG00845004737, ENSMMUG00000061127
|
| Target Classification |
GPCR, Checkpoint-Immuno Oncology
|
Pre-made viral vector of ADORA2B cDNA Clones/ORF Plasmid
ADORA2B siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo136 | Pre-made Human ADORA2B/ADORA2 siRNA oligo Duplex | 136 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29316 | Pre-made Rat Adora2b siRNA oligo Duplex | 29316 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11541 | Pre-made Mouse Adora2b/A2b/A2BR siRNA oligo Duplex | 11541 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696848 | Pre-made Cynomolgus/Rhesus macaque ADORA2B siRNA oligo Duplex | 696848 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo109494208 | Pre-made Cat/Feline ADORA2B siRNA oligo Duplex | 109494208 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403410 | Pre-made Dog/Canine ADORA2B siRNA oligo Duplex | 403410 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo529760 | Pre-made Bovines/Cattle ADORA2B siRNA oligo Duplex | 529760 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100063319 | Pre-made Equine/Horse ADORA2B siRNA oligo Duplex | 100063319 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ADORA2B antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T86679-Ab | Human | Anti-Human ADORA2B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T86679-Ab | Rat | Anti-Rat ADORA2B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T86679-Ab | Mouse | Anti-Mouse ADORA2B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T86679-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ADORA2B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T86679-Ab | Cat/Feline | Anti-Cat/Feline ADORA2B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T86679-Ab | Dog/Canine | Anti-Dog/Canine ADORA2B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T86679-Ab | Bovines/Cattle | Anti-Bovines/Cattle ADORA2B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T86679-Ab | Equine/Horse | Anti-Equine/Horse ADORA2B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ADORA2B VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T86679-Ag | Human | Human ADORA2B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T86679-Ag | Rat | Rat ADORA2B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T86679-Ag | Mouse | Mouse ADORA2B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T86679-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ADORA2B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T86679-Ag | Cat/Feline | Cat/Feline ADORA2B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T86679-Ag | Dog/Canine | Dog/Canine ADORA2B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T86679-Ag | Bovines/Cattle | Bovines/Cattle ADORA2B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T86679-Ag | Equine/Horse | Equine/Horse ADORA2B VLP (virus-like particle) | HEK293 | Products Developing |
