KCNN2 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore KCNN2 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]

Target ID GM-T86271
Target Name KCNN2
Gene Group ldentifer
(Target Gene ID in Homo species)
3781
Gene ID 100064342 (Equus caballus), 101099926 (Felis catus), 140492 (Mus musculus), 3781 (Homo sapiens)
404177 (Bos taurus), 474640 (Canis lupus familiaris), 54262 (Rattus norvegicus), 695374 (Macaca mulatta)
Target Alternative Names DYT34,KCNN2,KCa2.2,Kcnn2,NEDMAB,SK2,SKCA2,SKCa 2,SKCa2,Small conductance calcium-activated potassium channel protein 2,bc,fri,hSK2
Uniprot Accession P58390,Q9H2S1,P70604
Protein Sub-location Transmembrane Protein
Category Therapeutics Target
Disease from KEGG Serotonergic synapse, Insulin secretion, GnRH secretion, Bile secretion
Gene Ensembl ENSECAG00000020082, ENSMUSG00000054477, ENSG00000080709, ENSBTAG00000011076, ENSCAFG00845010795, ENSMMUG00000020502


Pre-made viral vector of KCNN2 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLPm005183Mouse Kcnn2/bc/fri Lentivirus plasmidXM_006525637.2140492MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLPm005183Mouse Kcnn2/bc/fri Lentivirus particleXM_006525637.2140492MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


KCNN2 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo3781Pre-made Human KCNN2/SK2/hSK2 siRNA oligo Duplex3781HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo54262Pre-made Rat Kcnn2/SK2/SKCa2 siRNA oligo Duplex54262RatIn-vitro grade; in-vivo gradeDetail
pGMoligo140492Pre-made Mouse Kcnn2/bc/SK2 siRNA oligo Duplex140492MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo695374Pre-made Cynomolgus/Rhesus macaque KCNN2 siRNA oligo Duplex695374Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101099926Pre-made Cat/Feline KCNN2 siRNA oligo Duplex101099926Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo474640Pre-made Dog/Canine KCNN2 siRNA oligo Duplex474640Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo404177Pre-made Bovines/Cattle KCNN2/SK2 siRNA oligo Duplex404177Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100064342Pre-made Equine/Horse KCNN2 siRNA oligo Duplex100064342Equine/HorseIn-vitro grade; in-vivo gradeDetail


KCNN2 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T86271-AbHumanAnti-Human KCNN2 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-rg-T86271-AbRatAnti-Rat KCNN2 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-mg-T86271-AbMouseAnti-Mouse KCNN2 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cynog-T86271-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque KCNN2 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-felg-T86271-AbCat/FelineAnti-Cat/Feline KCNN2 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cang-T86271-AbDog/CanineAnti-Dog/Canine KCNN2 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-bovg-T86271-AbBovines/CattleAnti-Bovines/Cattle KCNN2 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-equg-T86271-AbEquine/HorseAnti-Equine/Horse KCNN2 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail


KCNN2 VLP (virus-like particle)/protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T86271-AgHumanHuman KCNN2 VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-T86271-AgRatRat KCNN2 VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-T86271-AgMouseMouse KCNN2 VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-T86271-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque KCNN2 VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-T86271-AgCat/FelineCat/Feline KCNN2 VLP (virus-like particle)HEK293Products Developing
GM-Tg-cang-T86271-AgDog/CanineDog/Canine KCNN2 VLP (virus-like particle)HEK293Products Developing
GM-Tg-bovg-T86271-AgBovines/CattleBovines/Cattle KCNN2 VLP (virus-like particle)HEK293Products Developing
GM-Tg-equg-T86271-AgEquine/HorseEquine/Horse KCNN2 VLP (virus-like particle)HEK293Products Developing