Explore URAT1/SLC22A12 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
| Target ID |
GM-T86057
|
| Target Name |
URAT1/SLC22A12
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
116085
|
| Gene ID |
100055832 (Equus caballus), 101100592 (Felis catus), 116085 (Homo sapiens), 365398 (Rattus norvegicus)
483761 (Canis lupus familiaris), 526067 (Bos taurus), 717530 (Macaca mulatta)
|
| Target Alternative Names |
SLC22A12,Slc22a12,RST,UAT,OAT4L,URAT1,hURAT1,Rst,Slc22al2
|
| Uniprot Accession |
Q96S37,Q3ZAV1
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSG00000197891, ENSCAFG00845030289, ENSMMUG00000022594
|
| Target Classification |
|
Pre-made viral vector of URAT1/SLC22A12 cDNA Clones/ORF Plasmid
URAT1/SLC22A12 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo116085 | Pre-made Human SLC22A12/RST/UAT siRNA oligo Duplex | 116085 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo365398 | Pre-made Rat Slc22a12/Rst/URAT1 siRNA oligo Duplex | 365398 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717530 | Pre-made Cynomolgus/Rhesus macaque SLC22A12 siRNA oligo Duplex | 717530 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100592 | Pre-made Cat/Feline SLC22A12 siRNA oligo Duplex | 101100592 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483761 | Pre-made Dog/Canine SLC22A12/RST/OAT4L siRNA oligo Duplex | 483761 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo526067 | Pre-made Bovines/Cattle SLC22A12 siRNA oligo Duplex | 526067 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055832 | Pre-made Equine/Horse SLC22A12 siRNA oligo Duplex | 100055832 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
URAT1/SLC22A12 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T86057-Ab | Human | Anti-Human URAT1/SLC22A12 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T86057-Ab | Rat | Anti-Rat URAT1/SLC22A12 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T86057-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque URAT1/SLC22A12 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T86057-Ab | Cat/Feline | Anti-Cat/Feline URAT1/SLC22A12 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T86057-Ab | Dog/Canine | Anti-Dog/Canine URAT1/SLC22A12 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T86057-Ab | Bovines/Cattle | Anti-Bovines/Cattle URAT1/SLC22A12 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T86057-Ab | Equine/Horse | Anti-Equine/Horse URAT1/SLC22A12 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
URAT1/SLC22A12 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T86057-Ag | Human | Human URAT1/SLC22A12 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T86057-Ag | Rat | Rat URAT1/SLC22A12 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T86057-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque URAT1/SLC22A12 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T86057-Ag | Cat/Feline | Cat/Feline URAT1/SLC22A12 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T86057-Ag | Dog/Canine | Dog/Canine URAT1/SLC22A12 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T86057-Ag | Bovines/Cattle | Bovines/Cattle URAT1/SLC22A12 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T86057-Ag | Equine/Horse | Equine/Horse URAT1/SLC22A12 VLP (virus-like particle) | HEK293 | Products Developing |
