Explore c-SRC/SRC gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T85943
|
| Target Name |
c-SRC/SRC
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6714
|
| Gene ID |
100069870 (Equus caballus), 101100378 (Felis catus), 20779 (Mus musculus), 485864 (Canis lupus familiaris)
535742 (Bos taurus), 6714 (Homo sapiens), 701057 (Macaca mulatta), 83805 (Rattus norvegicus)
|
| Target Alternative Names |
ASV,Proto-oncogene c-Src,Proto-oncogene tyrosine-protein kinase Src,SRC,SRC1,Src,THC6,c-SRC,p60-Src,pp60c-src,pp60c-src (p60-Src)
|
| Uniprot Accession |
P05480,P12931,Q9WUD9
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Rap1 signaling pathway, Chemokine signaling pathway, Axon guidance, Focal adhesion, Adherens junction, Tight junction, Gap junction, Platelet activation, C-type lectin receptor signaling pathway, GABAergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, GnRH signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Yersinia infection, Tuberculosis, Hepatitis B, Human cytomegalovirus infection, Kaposi sarcoma-associated herpesvirus infection, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Bladder cancer, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000012072, ENSMUSG00000027646, ENSCAFG00845028314, ENSBTAG00000008938, ENSG00000197122, ENSMMUG00000020131
|
| Target Classification |
Kinase, Tumor-associated antigen (TAA)
|
Pre-made viral vector of c-SRC/SRC cDNA Clones/ORF Plasmid
c-SRC/SRC siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6714 | Pre-made Human SRC/ASV/SRC1 siRNA oligo Duplex | 6714 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo83805 | Pre-made Rat Src siRNA oligo Duplex | 83805 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20779 | Pre-made Mouse Src/pp60c-src siRNA oligo Duplex | 20779 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701057 | Pre-made Cynomolgus/Rhesus macaque SRC siRNA oligo Duplex | 701057 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100378 | Pre-made Cat/Feline SRC siRNA oligo Duplex | 101100378 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485864 | Pre-made Dog/Canine SRC siRNA oligo Duplex | 485864 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo535742 | Pre-made Bovines/Cattle SRC siRNA oligo Duplex | 535742 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100069870 | Pre-made Equine/Horse SRC siRNA oligo Duplex | 100069870 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
c-SRC/SRC antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T85943-Ab | Human | Anti-Human c-SRC/SRC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T85943-Ab | Rat | Anti-Rat c-SRC/SRC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T85943-Ab | Mouse | Anti-Mouse c-SRC/SRC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T85943-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque c-SRC/SRC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T85943-Ab | Cat/Feline | Anti-Cat/Feline c-SRC/SRC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T85943-Ab | Dog/Canine | Anti-Dog/Canine c-SRC/SRC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T85943-Ab | Bovines/Cattle | Anti-Bovines/Cattle c-SRC/SRC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T85943-Ab | Equine/Horse | Anti-Equine/Horse c-SRC/SRC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
c-SRC/SRC VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T85943-Ag | Human | Human c-SRC/SRC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T85943-Ag | Rat | Rat c-SRC/SRC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T85943-Ag | Mouse | Mouse c-SRC/SRC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T85943-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque c-SRC/SRC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T85943-Ag | Cat/Feline | Cat/Feline c-SRC/SRC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T85943-Ag | Dog/Canine | Dog/Canine c-SRC/SRC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T85943-Ag | Bovines/Cattle | Bovines/Cattle c-SRC/SRC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T85943-Ag | Equine/Horse | Equine/Horse c-SRC/SRC VLP (virus-like particle) | HEK293 | Products Developing |
