Explore RANK/TNFRSF11A/CD265/ODFR gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2012]
| Target ID |
GM-T85746
|
| Target Name |
RANK/TNFRSF11A/CD265/ODFR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8792
|
| Gene ID |
100056617 (Equus caballus), 100424175 (Macaca mulatta), 101090651 (Felis catus), 21934 (Mus musculus)
483957 (Canis lupus familiaris), 498206 (Rattus norvegicus), 530884 (Bos taurus), 8792 (Homo sapiens)
|
| Target Alternative Names |
CD265,FEO,LOH18CR1,Ly109,ODFR,OFE,OPTB7,OSTS,Osteoclast differentiation factor receptor (ODFR),PDB2,RANK,RGD1563614,Rank,Receptor activator of NF-KB,TNFRSF11A,TRANCE-R,TRANCER,Tnfrsf11a,Tumor necrosis factor receptor superfamily member 11A,mRANK
|
| Uniprot Accession |
O35305,Q9Y6Q6
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Prolactin signaling pathway, Rheumatoid arthritis
|
| Gene Ensembl |
ENSECAG00000014672, ENSMMUG00000002210, ENSMUSG00000026321, ENSCAFG00845000032, ENSBTAG00000007569, ENSG00000141655
|
| Target Classification |
Pathway, Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
Pre-made viral vector of RANK/TNFRSF11A/CD265/ODFR cDNA Clones/ORF Plasmid
RANK/TNFRSF11A/CD265/ODFR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8792 | Pre-made Human TNFRSF11A/FEO/OFE siRNA oligo Duplex | 8792 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo498206 | Pre-made Rat Tnfrsf11a/RANK/RGD1563614 siRNA oligo Duplex | 498206 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21934 | Pre-made Mouse Tnfrsf11a/OFE/ODFR siRNA oligo Duplex | 21934 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100424175 | Pre-made Cynomolgus/Rhesus macaque TNFRSF11A siRNA oligo Duplex | 100424175 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090651 | Pre-made Cat/Feline TNFRSF11A siRNA oligo Duplex | 101090651 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483957 | Pre-made Dog/Canine TNFRSF11A/RANK siRNA oligo Duplex | 483957 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo530884 | Pre-made Bovines/Cattle TNFRSF11A siRNA oligo Duplex | 530884 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056617 | Pre-made Equine/Horse TNFRSF11A siRNA oligo Duplex | 100056617 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RANK/TNFRSF11A/CD265/ODFR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T85746-Ab | Human | Anti-Human RANK/TNFRSF11A/CD265/ODFR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T85746-Ab | Rat | Anti-Rat RANK/TNFRSF11A/CD265/ODFR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T85746-Ab | Mouse | Anti-Mouse RANK/TNFRSF11A/CD265/ODFR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T85746-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RANK/TNFRSF11A/CD265/ODFR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T85746-Ab | Cat/Feline | Anti-Cat/Feline RANK/TNFRSF11A/CD265/ODFR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T85746-Ab | Dog/Canine | Anti-Dog/Canine RANK/TNFRSF11A/CD265/ODFR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T85746-Ab | Bovines/Cattle | Anti-Bovines/Cattle RANK/TNFRSF11A/CD265/ODFR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T85746-Ab | Equine/Horse | Anti-Equine/Horse RANK/TNFRSF11A/CD265/ODFR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
RANK/TNFRSF11A/CD265/ODFR VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T85746-Ag | Human | Human RANK/TNFRSF11A/CD265/ODFR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T85746-Ag | Rat | Rat RANK/TNFRSF11A/CD265/ODFR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T85746-Ag | Mouse | Mouse RANK/TNFRSF11A/CD265/ODFR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T85746-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RANK/TNFRSF11A/CD265/ODFR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T85746-Ag | Cat/Feline | Cat/Feline RANK/TNFRSF11A/CD265/ODFR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T85746-Ag | Dog/Canine | Dog/Canine RANK/TNFRSF11A/CD265/ODFR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T85746-Ag | Bovines/Cattle | Bovines/Cattle RANK/TNFRSF11A/CD265/ODFR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T85746-Ag | Equine/Horse | Equine/Horse RANK/TNFRSF11A/CD265/ODFR VLP (virus-like particle) | HEK293 | Products Developing |
