Explore TRPM5 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele. [provided by RefSeq, Oct 2010]
| Target ID |
GM-T85545
|
| Target Name |
TRPM5
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
29850
|
| Gene ID |
100060376 (Equus caballus), 100299596 (Bos taurus), 101092891 (Felis catus), 29850 (Homo sapiens) 365391 (Rattus norvegicus), 483668 (Canis lupus familiaris), 56843 (Mus musculus), 705070 (Macaca mulatta)
|
| Target Alternative Names |
9430099A16Rik,LTRPC5,LTrpC-5,LTrpC5),Long transient receptor potential channel 5 (LTrpC-5,Ltrpc5,MLSN1- and TRP-related gene 1 protein,MTR1,Mtr1,TRPM5,Transient receptor potential cation channel subfamily M member 5,Trpm5
|
| Uniprot Accession |
Q9NZQ8,Q9JJH7
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Taste transduction
|
| Gene Ensembl |
ENSECAG00000024688, ENSBTAG00000046662, ENSG00000070985, ENSCAFG00845011524, ENSMUSG00000009246, ENSMMUG00000004773
|
TRPM5 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo29850 | Pre-made Human TRPM5/MTR1/LTRPC5 siRNA oligo Duplex | 29850 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo365391 | Pre-made Rat Trpm5 siRNA oligo Duplex | 365391 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo56843 | Pre-made Mouse Trpm5/Mtr1/Ltrpc5 siRNA oligo Duplex | 56843 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705070 | Pre-made Cynomolgus/Rhesus macaque TRPM5 siRNA oligo Duplex | 705070 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092891 | Pre-made Cat/Feline TRPM5 siRNA oligo Duplex | 101092891 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483668 | Pre-made Dog/Canine TRPM5 siRNA oligo Duplex | 483668 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100299596 | Pre-made Bovines/Cattle TRPM5 siRNA oligo Duplex | 100299596 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060376 | Pre-made Equine/Horse TRPM5 siRNA oligo Duplex | 100060376 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TRPM5 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T85545-Ab | Human | Anti-Human TRPM5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T85545-Ab | Rat | Anti-Rat TRPM5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T85545-Ab | Mouse | Anti-Mouse TRPM5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T85545-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TRPM5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T85545-Ab | Cat/Feline | Anti-Cat/Feline TRPM5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T85545-Ab | Dog/Canine | Anti-Dog/Canine TRPM5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T85545-Ab | Bovines/Cattle | Anti-Bovines/Cattle TRPM5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T85545-Ab | Equine/Horse | Anti-Equine/Horse TRPM5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
TRPM5 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T85545-Ag | Human | Human TRPM5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T85545-Ag | Rat | Rat TRPM5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T85545-Ag | Mouse | Mouse TRPM5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T85545-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TRPM5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T85545-Ag | Cat/Feline | Cat/Feline TRPM5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T85545-Ag | Dog/Canine | Dog/Canine TRPM5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T85545-Ag | Bovines/Cattle | Bovines/Cattle TRPM5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T85545-Ag | Equine/Horse | Equine/Horse TRPM5 VLP (virus-like particle) | HEK293 | Products Developing |