Explore KDM5C gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling. Mutations in this gene have been associated with X-linked cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
| Target ID |
GM-T85540
|
| Target Name |
KDM5C
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
8242
|
| Gene ID |
100034190 (Equus caballus), 101091600 (Felis catus), 106992262 (Macaca mulatta), 20591 (Mus musculus) 281490 (Bos taurus), 317432 (Rattus norvegicus), 491894 (Canis lupus familiaris), 8242 (Homo sapiens)
|
| Target Alternative Names |
D930009K15Rik,DXS1272E,Histone demethylase JARID1C,JARID1C,Jarid1c,Jumonji/ARID domain-containing protein 1C,KDM5C,Kdm5c,Lysine-specific demethylase 5C,MRX13,MRXJ,MRXSCJ,MRXSJ,Protein SmcX,Protein Xe169,RGD1560601,SMCX,Smcx,XE169,[histone H3]-trimethyl-L-lysine(4) demethylase 5C,mKIAA0234
|
| Uniprot Accession |
P41230,Q38JA7,P41229
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000024956, ENSMMUG00000020553, ENSMUSG00000025332, ENSBTAG00000014943, ENSCAFG00845028407, ENSG00000126012
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of KDM5C cDNA Clones/ORF Plasmid
KDM5C siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8242 | Pre-made Human KDM5C/MRXJ/SMCX siRNA oligo Duplex | 8242 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo317432 | Pre-made Rat Kdm5c/RGD1560601 siRNA oligo Duplex | 317432 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20591 | Pre-made Mouse Kdm5c/Smcx/Jarid1c siRNA oligo Duplex | 20591 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo106992262 | Pre-made Cynomolgus/Rhesus macaque KDM5C/JARID1C siRNA oligo Duplex | 106992262 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091600 | Pre-made Cat/Feline KDM5C/SMCX siRNA oligo Duplex | 101091600 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo491894 | Pre-made Dog/Canine KDM5C/SMCX/JARID1C siRNA oligo Duplex | 491894 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281490 | Pre-made Bovines/Cattle KDM5C/SMCX/JARID1C siRNA oligo Duplex | 281490 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034190 | Pre-made Equine/Horse KDM5C/SMCX/JARID1C siRNA oligo Duplex | 100034190 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KDM5C antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T85540-Ab | Human | Anti-Human KDM5C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T85540-Ab | Rat | Anti-Rat KDM5C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T85540-Ab | Mouse | Anti-Mouse KDM5C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T85540-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KDM5C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T85540-Ab | Cat/Feline | Anti-Cat/Feline KDM5C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T85540-Ab | Dog/Canine | Anti-Dog/Canine KDM5C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T85540-Ab | Bovines/Cattle | Anti-Bovines/Cattle KDM5C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T85540-Ab | Equine/Horse | Anti-Equine/Horse KDM5C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
KDM5C recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T85540-Ag | Human | Human KDM5C recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T85540-Ag | Rat | Rat KDM5C recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T85540-Ag | Mouse | Mouse KDM5C recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T85540-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KDM5C recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T85540-Ag | Cat/Feline | Cat/Feline KDM5C recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T85540-Ag | Dog/Canine | Dog/Canine KDM5C recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T85540-Ag | Bovines/Cattle | Bovines/Cattle KDM5C recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T85540-Ag | Equine/Horse | Equine/Horse KDM5C recombinant protein | Mammalian cell | Detail |