Explore MYBPC3 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3 is expressed exclusively in heart muscle and is a key regulator of cardiac contraction. Mutations in this gene are a frequent cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, May 2022]
| Target ID |
GM-T85523
|
| Target Name |
MYBPC3
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4607
|
| Gene ID |
100057959 (Equus caballus), 101094698 (Felis catus), 17868 (Mus musculus), 295929 (Rattus norvegicus) 4607 (Homo sapiens), 483624 (Canis lupus familiaris), 712093 (Macaca mulatta), 767614 (Bos taurus)
|
| Target Alternative Names |
C-protein,CMD1MM,CMH4,Cardiac MyBP-C,FHC,LVNC10,MYBP-C,MYBPC3,Mybpc3,Myosin-binding protein C,cMyBP-C,cardiac muscle isoform,cardiac-type
|
| Uniprot Accession |
O70468,P56741,Q14896
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Hypertrophic cardiomyopathy, Dilated cardiomyopathy
|
| Gene Ensembl |
ENSECAG00000024318, ENSMUSG00000002100, ENSG00000134571, ENSCAFG00845021902, ENSMMUG00000015604, ENSBTAG00000021707
|
MYBPC3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4607 | Pre-made Human MYBPC3/FHC/CMH4 siRNA oligo Duplex | 4607 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo295929 | Pre-made Rat Mybpc3 siRNA oligo Duplex | 295929 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17868 | Pre-made Mouse Mybpc3 siRNA oligo Duplex | 17868 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712093 | Pre-made Cynomolgus/Rhesus macaque MYBPC3 siRNA oligo Duplex | 712093 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094698 | Pre-made Cat/Feline MYBPC3 siRNA oligo Duplex | 101094698 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483624 | Pre-made Dog/Canine MYBPC3 siRNA oligo Duplex | 483624 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo767614 | Pre-made Bovines/Cattle MYBPC3 siRNA oligo Duplex | 767614 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100057959 | Pre-made Equine/Horse MYBPC3 siRNA oligo Duplex | 100057959 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MYBPC3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T85523-Ab | Human | Anti-Human MYBPC3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T85523-Ab | Rat | Anti-Rat MYBPC3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T85523-Ab | Mouse | Anti-Mouse MYBPC3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T85523-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MYBPC3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T85523-Ab | Cat/Feline | Anti-Cat/Feline MYBPC3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T85523-Ab | Dog/Canine | Anti-Dog/Canine MYBPC3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T85523-Ab | Bovines/Cattle | Anti-Bovines/Cattle MYBPC3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T85523-Ab | Equine/Horse | Anti-Equine/Horse MYBPC3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
MYBPC3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T85523-Ag | Human | Human MYBPC3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T85523-Ag | Rat | Rat MYBPC3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T85523-Ag | Mouse | Mouse MYBPC3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T85523-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MYBPC3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T85523-Ag | Cat/Feline | Cat/Feline MYBPC3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T85523-Ag | Dog/Canine | Dog/Canine MYBPC3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T85523-Ag | Bovines/Cattle | Bovines/Cattle MYBPC3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T85523-Ag | Equine/Horse | Equine/Horse MYBPC3 recombinant protein | Mammalian cell | Detail |