Explore IL-7Ra/CD127/IL7R gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found. [provided by RefSeq, Dec 2015]
| Target ID |
GM-T85025
|
| Target Name |
IL-7Ra/CD127/IL7R
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3575
|
| Gene ID |
100034169 (Equus caballus), 101100697 (Felis catus), 16197 (Mus musculus), 294797 (Rattus norvegicus)
3575 (Homo sapiens), 521554 (Bos taurus), 612582 (Canis lupus familiaris), 699869 (Macaca mulatta)
|
| Target Alternative Names |
CD127,CDW127,CDw127,IL-7 receptor subunit alpha,IL-7R subunit alpha,IL-7R-alpha,IL-7RA,IL-7Ra,IL-7Ralpha,IL7R,IL7RA,IL7Ralpha,ILRA,IMD104,Il7r,Interleukin-7 receptor subunit alpha,lnc-IL7R,sIL-7R
|
| Uniprot Accession |
A0MSX9,P16872,P16871
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, FoxO signaling pathway, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer
|
| Gene Ensembl |
ENSECAG00000033707, ENSMUSG00000003882, ENSG00000168685, ENSBTAG00000019975, ENSCAFG00845000499, ENSMMUG00000001676
|
| Target Classification |
Cytokine Receptor, Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
Pre-made viral vector of IL-7Ra/CD127/IL7R cDNA Clones/ORF Plasmid
IL-7Ra/CD127/IL7R siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3575 | Pre-made Human IL7R/ILRA/CD127 siRNA oligo Duplex | 3575 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo294797 | Pre-made Rat Il7r siRNA oligo Duplex | 294797 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16197 | Pre-made Mouse Il7r/CD127/IL-7Ralpha siRNA oligo Duplex | 16197 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699869 | Pre-made Cynomolgus/Rhesus macaque IL7R siRNA oligo Duplex | 699869 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100697 | Pre-made Cat/Feline IL7R siRNA oligo Duplex | 101100697 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo612582 | Pre-made Dog/Canine IL7R siRNA oligo Duplex | 612582 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo521554 | Pre-made Bovines/Cattle IL7R siRNA oligo Duplex | 521554 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034169 | Pre-made Equine/Horse IL7R/IL-7RA siRNA oligo Duplex | 100034169 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-7Ra/CD127/IL7R antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T85025-Ab | Human | Anti-Human IL-7Ra/CD127/IL7R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T85025-Ab | Rat | Anti-Rat IL-7Ra/CD127/IL7R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T85025-Ab | Mouse | Anti-Mouse IL-7Ra/CD127/IL7R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T85025-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-7Ra/CD127/IL7R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T85025-Ab | Cat/Feline | Anti-Cat/Feline IL-7Ra/CD127/IL7R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T85025-Ab | Dog/Canine | Anti-Dog/Canine IL-7Ra/CD127/IL7R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T85025-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-7Ra/CD127/IL7R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T85025-Ab | Equine/Horse | Anti-Equine/Horse IL-7Ra/CD127/IL7R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
IL-7Ra/CD127/IL7R VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T85025-Ag | Human | Human IL-7Ra/CD127/IL7R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T85025-Ag | Rat | Rat IL-7Ra/CD127/IL7R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T85025-Ag | Mouse | Mouse IL-7Ra/CD127/IL7R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T85025-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-7Ra/CD127/IL7R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T85025-Ag | Cat/Feline | Cat/Feline IL-7Ra/CD127/IL7R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T85025-Ag | Dog/Canine | Dog/Canine IL-7Ra/CD127/IL7R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T85025-Ag | Bovines/Cattle | Bovines/Cattle IL-7Ra/CD127/IL7R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T85025-Ag | Equine/Horse | Equine/Horse IL-7Ra/CD127/IL7R VLP (virus-like particle) | HEK293 | Products Developing |
