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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T84621
|
| Target Name |
CYP11B1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1584
|
| Gene ID |
1584 (Homo sapiens)
|
| Target Alternative Names |
CPN1,CYP11B,CYP11B1,CYPXIB1,Cytochrome P-450c11 (Cytochrome P450C11),Cytochrome P450 11B1,FHI,P450C11,Steroid 11-beta-hydroxylase,mitochondrial
|
| Uniprot Accession |
P15538
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Metabolic pathways, Steroid hormone biosynthesis, Cortisol synthesis and secretion, Cushing syndrome
|
| Gene Ensembl |
ENSG00000160882
|
| Target Classification |
Tumor-associated antigen (TAA)
|
CYP11B1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1584 | Pre-made Human CYP11B1/FHI/CPN1 siRNA oligo Duplex | 1584 | Human | In-vitro grade; in-vivo grade | Detail |
CYP11B1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T84621-Ab | Human | Anti-Human CYP11B1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
CYP11B1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T84621-Ag | Human | Human CYP11B1 recombinant protein | Mammalian cell | Detail |
