Explore Alpha Sarcoglycan/SGCA gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
| Target ID |
GM-T84584
|
| Target Name |
Alpha Sarcoglycan/SGCA
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6442
|
| Gene ID |
100056285 (Equus caballus), 101092469 (Felis catus), 20391 (Mus musculus), 303468 (Rattus norvegicus)
541308 (Bos taurus), 609265 (Canis lupus familiaris), 6442 (Homo sapiens), 704493 (Macaca mulatta)
|
| Target Alternative Names |
50 kDa dystrophin-associated glycoprotein (50DAG),50DAG,ADL,Adhalin,Alpha Sarcoglycan,Alpha-SG,Alpha-sarcoglycan,Asg,DAG2,DMDA2,Dystroglycan-2,LGMD2D,LGMDR3,SCARMD1,SGCA,Sgca,adhalin
|
| Uniprot Accession |
P82350,Q16586
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
Prostate Cancer
|
| Disease from KEGG |
Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Viral myocarditis
|
| Gene Ensembl |
ENSECAG00000047470, ENSMUSG00000001508, ENSBTAG00000003956, ENSCAFG00845012386, ENSG00000108823, ENSMMUG00000001466
|
Pre-made viral vector of Alpha Sarcoglycan/SGCA cDNA Clones/ORF Plasmid
Alpha Sarcoglycan/SGCA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6442 | Pre-made Human SGCA/ADL/DAG2 siRNA oligo Duplex | 6442 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo303468 | Pre-made Rat Sgca siRNA oligo Duplex | 303468 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20391 | Pre-made Mouse Sgca/Asg/50DAG siRNA oligo Duplex | 20391 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704493 | Pre-made Cynomolgus/Rhesus macaque SGCA siRNA oligo Duplex | 704493 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092469 | Pre-made Cat/Feline SGCA siRNA oligo Duplex | 101092469 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo609265 | Pre-made Dog/Canine SGCA siRNA oligo Duplex | 609265 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo541308 | Pre-made Bovines/Cattle SGCA siRNA oligo Duplex | 541308 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056285 | Pre-made Equine/Horse SGCA siRNA oligo Duplex | 100056285 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Alpha Sarcoglycan/SGCA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T84584-Ab | Human | Anti-Human Alpha Sarcoglycan/SGCA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T84584-Ab | Rat | Anti-Rat Alpha Sarcoglycan/SGCA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T84584-Ab | Mouse | Anti-Mouse Alpha Sarcoglycan/SGCA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T84584-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Alpha Sarcoglycan/SGCA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T84584-Ab | Cat/Feline | Anti-Cat/Feline Alpha Sarcoglycan/SGCA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T84584-Ab | Dog/Canine | Anti-Dog/Canine Alpha Sarcoglycan/SGCA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T84584-Ab | Bovines/Cattle | Anti-Bovines/Cattle Alpha Sarcoglycan/SGCA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T84584-Ab | Equine/Horse | Anti-Equine/Horse Alpha Sarcoglycan/SGCA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Alpha Sarcoglycan/SGCA recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T84584-Ag | Human | Human Alpha Sarcoglycan/SGCA recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T84584-Ag | Rat | Rat Alpha Sarcoglycan/SGCA recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T84584-Ag | Mouse | Mouse Alpha Sarcoglycan/SGCA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T84584-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Alpha Sarcoglycan/SGCA recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T84584-Ag | Cat/Feline | Cat/Feline Alpha Sarcoglycan/SGCA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T84584-Ag | Dog/Canine | Dog/Canine Alpha Sarcoglycan/SGCA recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T84584-Ag | Bovines/Cattle | Bovines/Cattle Alpha Sarcoglycan/SGCA recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T84584-Ag | Equine/Horse | Equine/Horse Alpha Sarcoglycan/SGCA recombinant protein | Mammalian cell | Detail |
