Explore P-cadherin/CDH3 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015]
| Target ID |
GM-T83905
|
| Target Name |
P-cadherin/CDH3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1001
|
| Gene ID |
100066779 (Equus caballus), 1001 (Homo sapiens), 101094895 (Felis catus), 116777 (Rattus norvegicus)
12560 (Mus musculus), 281063 (Bos taurus), 611010 (Canis lupus familiaris), 703324 (Macaca mulatta)
|
| Target Alternative Names |
CDH3,Cdh3,CDHP,HJMD,PCAD,Cadp,Cdhp,Pcad,P-cadherin
|
| Uniprot Accession |
P22223,P10287,P19535
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
cancer, Breast Cancer, Breast Cancer
|
| Disease from KEGG |
Cell adhesion molecules
|
| Gene Ensembl |
ENSECAG00000009528, ENSG00000062038, ENSMUSG00000061048, ENSBTAG00000033248, ENSCAFG00845010963, ENSMMUG00000010393
|
| Target Classification |
Checkpoint-Immuno Oncology
|
P-cadherin/CDH3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1001 | Pre-made Human CDH3/CDHP/HJMD siRNA oligo Duplex | 1001 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo116777 | Pre-made Rat Cdh3 siRNA oligo Duplex | 116777 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12560 | Pre-made Mouse Cdh3/Cadp/Cdhp siRNA oligo Duplex | 12560 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703324 | Pre-made Cynomolgus/Rhesus macaque CDH3 siRNA oligo Duplex | 703324 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094895 | Pre-made Cat/Feline CDH3 siRNA oligo Duplex | 101094895 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611010 | Pre-made Dog/Canine CDH3 siRNA oligo Duplex | 611010 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281063 | Pre-made Bovines/Cattle CDH3 siRNA oligo Duplex | 281063 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066779 | Pre-made Equine/Horse CDH3 siRNA oligo Duplex | 100066779 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
P-cadherin/CDH3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T83905-Ab | Human | Anti-Human P-cadherin/CDH3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T83905-Ab | Rat | Anti-Rat P-cadherin/CDH3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T83905-Ab | Mouse | Anti-Mouse P-cadherin/CDH3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T83905-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque P-cadherin/CDH3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T83905-Ab | Cat/Feline | Anti-Cat/Feline P-cadherin/CDH3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T83905-Ab | Dog/Canine | Anti-Dog/Canine P-cadherin/CDH3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T83905-Ab | Bovines/Cattle | Anti-Bovines/Cattle P-cadherin/CDH3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T83905-Ab | Equine/Horse | Anti-Equine/Horse P-cadherin/CDH3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
P-cadherin/CDH3 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T83905-Ag | Human | Human P-cadherin/CDH3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T83905-Ag | Rat | Rat P-cadherin/CDH3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T83905-Ag | Mouse | Mouse P-cadherin/CDH3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T83905-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque P-cadherin/CDH3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T83905-Ag | Cat/Feline | Cat/Feline P-cadherin/CDH3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T83905-Ag | Dog/Canine | Dog/Canine P-cadherin/CDH3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T83905-Ag | Bovines/Cattle | Bovines/Cattle P-cadherin/CDH3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T83905-Ag | Equine/Horse | Equine/Horse P-cadherin/CDH3 VLP (virus-like particle) | HEK293 | Products Developing |
