HTR2C Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore HTR2C gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
This gene encodes a seven-transmembrane G-protein-coupled receptor. The encoded protein responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants. [provided by RefSeq, Jan 2015]

Target ID GM-T83813
Target Name HTR2C
Gene Group ldentifer
(Target Gene ID in Homo species)
3358
Gene ID 100057852 (Equus caballus), 101099620 (Felis catus), 15560 (Mus musculus), 25187 (Rattus norvegicus)
3358 (Homo sapiens), 407134 (Bos taurus), 450240 (Canis lupus familiaris), 708141 (Macaca mulatta)
Target Alternative Names 5-HT-1C,5-HT-2C,5-HT1C,5-HT1C),5-HT2C,5-HT2cR,5-HTR2C,5-hydroxytryptamine receptor 1C (5-HT-1C,5-hydroxytryptamine receptor 2C,5HT-1C,5HT1c,5HT2C,5HTR2C,5htr2c,HTR1C,HTR2C,Htr1c,Htr2c,SR1,Serotonin receptor 2C
Uniprot Accession P34968,P08909,P28335,Q60F97
Protein Sub-location Transmembrane Protein
Category Therapeutics Target
Disease from KEGG Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels
Gene Ensembl ENSECAG00000021540, ENSMUSG00000041380, ENSG00000147246, ENSCAFG00845015792, ENSMMUG00000009607
Target Classification GPCR


Pre-made viral vector of HTR2C cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP003724Human HTR2C/5-HT1C/5-HT2C Lentivirus plasmidNM_0008683358HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP003724Human HTR2C/5-HT1C/5-HT2C Lentivirus particleNM_0008683358HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMAAV000984Mouse Htr2c/5-HT2C/5-HT2cR Adeno-associate virus(AAV) plasmidNM_008312.415560MouseAdeno-associate virus(AAV) plasmidZsGreen3xflag (C-Terminal)CAGDetail
pGMLPm005395Mouse Htr2c/5-HT2C/5-HT2cR Lentivirus plasmidXM_017318391.115560MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMAAV000984Mouse Htr2c/5-HT2C/5-HT2cR Adeno-associate virus(AAV) particleNM_008312.415560MouseAdeno-associate virus(AAV) particleZsGreen3xflag (C-Terminal)CAGDetail
vGMLPm005395Mouse Htr2c/5-HT2C/5-HT2cR Lentivirus particleXM_017318391.115560MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


HTR2C siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo3358Pre-made Human HTR2C/HTR1C/5-HT1C siRNA oligo Duplex3358HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo25187Pre-made Rat Htr2c/5-HT2C/5HT-1C siRNA oligo Duplex25187RatIn-vitro grade; in-vivo gradeDetail
pGMoligo15560Pre-made Mouse Htr2c/SR1/5HT1c siRNA oligo Duplex15560MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo708141Pre-made Cynomolgus/Rhesus macaque HTR2C siRNA oligo Duplex708141Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101099620Pre-made Cat/Feline HTR2C siRNA oligo Duplex101099620Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo450240Pre-made Dog/Canine HTR2C/5-HT-2C/5-HTR2C siRNA oligo Duplex450240Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo407134Pre-made Bovines/Cattle HTR2C/5HT2C/5-HT2C siRNA oligo Duplex407134Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100057852Pre-made Equine/Horse HTR2C siRNA oligo Duplex100057852Equine/HorseIn-vitro grade; in-vivo gradeDetail


HTR2C antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T83813-AbHumanAnti-Human HTR2C monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-rg-T83813-AbRatAnti-Rat HTR2C monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-mg-T83813-AbMouseAnti-Mouse HTR2C monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cynog-T83813-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque HTR2C monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-felg-T83813-AbCat/FelineAnti-Cat/Feline HTR2C monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cang-T83813-AbDog/CanineAnti-Dog/Canine HTR2C monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-bovg-T83813-AbBovines/CattleAnti-Bovines/Cattle HTR2C monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-equg-T83813-AbEquine/HorseAnti-Equine/Horse HTR2C monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail


HTR2C VLP (virus-like particle)/protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T83813-AgHumanHuman HTR2C VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-T83813-AgRatRat HTR2C VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-T83813-AgMouseMouse HTR2C VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-T83813-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque HTR2C VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-T83813-AgCat/FelineCat/Feline HTR2C VLP (virus-like particle)HEK293Products Developing
GM-Tg-cang-T83813-AgDog/CanineDog/Canine HTR2C VLP (virus-like particle)HEK293Products Developing
GM-Tg-bovg-T83813-AgBovines/CattleBovines/Cattle HTR2C VLP (virus-like particle)HEK293Products Developing
GM-Tg-equg-T83813-AgEquine/HorseEquine/Horse HTR2C VLP (virus-like particle)HEK293Products Developing