Factor IX/PTC/F9 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore Factor IX/PTC/F9 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Sep 2015]

Pre-made viral vector of Factor IX/PTC/F9 cDNA Clones/ORF Plasmid

Factor IX/PTC/F9 siRNA/miRNA/oligo for RNA interfence (RNAi)

Factor IX/PTC/F9 antibody/GMab

Factor IX/PTC/F9 VLP (virus-like particle)/protein