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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T83193
|
| Target Name |
TRPV1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7442
|
| Gene ID |
100034158 (Equus caballus), 101093406 (Felis catus), 107131508 (Bos taurus), 193034 (Mus musculus)
445457 (Canis lupus familiaris), 721455 (Macaca mulatta), 7442 (Homo sapiens), 83810 (Rattus norvegicus)
|
| Target Alternative Names |
Capsaicin receptor,OTRPC1,Osm-9-like TRP channel 1 (OTRPC1),TRPV1,TRPV1_SON,TRPV1alpha,TRPV1beta,Transient receptor potential cation channel subfamily V member 1,TrpV1,Trpv1,VR-1,VR.5'sv,VR1,Vanilloid receptor 1,Vr1,Vr1l1
|
| Uniprot Accession |
Q704Y3,Q697L1,Q8NER1,O35433
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction, Inflammatory mediator regulation of TRP channels
|
| Gene Ensembl |
ENSECAG00000022758, ENSBTAG00000018880, ENSMUSG00000005952, ENSCAFG00845015972, ENSMMUG00000000711, ENSG00000196689
|
| Target Classification |
Ion Channel
|
Pre-made viral vector of TRPV1 cDNA Clones/ORF Plasmid
TRPV1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7442 | Pre-made Human TRPV1/VR1 siRNA oligo Duplex | 7442 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo83810 | Pre-made Rat Trpv1/Vr1/Vr1l1 siRNA oligo Duplex | 83810 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo193034 | Pre-made Mouse Trpv1/Vr1/VR-1 siRNA oligo Duplex | 193034 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo721455 | Pre-made Cynomolgus/Rhesus macaque TRPV1 siRNA oligo Duplex | 721455 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093406 | Pre-made Cat/Feline TRPV1 siRNA oligo Duplex | 101093406 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo445457 | Pre-made Dog/Canine TRPV1/VR1 siRNA oligo Duplex | 445457 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo107131508 | Pre-made Bovines/Cattle TRPV1 siRNA oligo Duplex | 107131508 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034158 | Pre-made Equine/Horse TRPV1 siRNA oligo Duplex | 100034158 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TRPV1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T83193-Ab | Human | Anti-Human TRPV1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T83193-Ab | Rat | Anti-Rat TRPV1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T83193-Ab | Mouse | Anti-Mouse TRPV1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T83193-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TRPV1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T83193-Ab | Cat/Feline | Anti-Cat/Feline TRPV1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T83193-Ab | Dog/Canine | Anti-Dog/Canine TRPV1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T83193-Ab | Bovines/Cattle | Anti-Bovines/Cattle TRPV1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T83193-Ab | Equine/Horse | Anti-Equine/Horse TRPV1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
TRPV1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T83193-Ag | Human | Human TRPV1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T83193-Ag | Rat | Rat TRPV1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T83193-Ag | Mouse | Mouse TRPV1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T83193-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TRPV1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T83193-Ag | Cat/Feline | Cat/Feline TRPV1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T83193-Ag | Dog/Canine | Dog/Canine TRPV1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T83193-Ag | Bovines/Cattle | Bovines/Cattle TRPV1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T83193-Ag | Equine/Horse | Equine/Horse TRPV1 VLP (virus-like particle) | HEK293 | Products Developing |
