Explore ABL2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009]
| Target ID |
GM-T83009
|
| Target Name |
ABL2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
27
|
| Gene ID |
100053033 (Equus caballus), 101080757 (Felis catus), 11352 (Mus musculus), 27 (Homo sapiens)
304883 (Rattus norvegicus), 480052 (Canis lupus familiaris), 511845 (Bos taurus), 717037 (Macaca mulatta)
|
| Target Alternative Names |
ABL2,Abl2,Arg,Abll,ARG,ABLL
|
| Uniprot Accession |
Q4JIM5,P42684
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
ErbB signaling pathway, Ras signaling pathway, Viral myocarditis
|
| Gene Ensembl |
ENSECAG00000005708, ENSMUSG00000026596, ENSG00000143322, ENSCAFG00845006265, ENSBTAG00000015026, ENSMMUG00000006262
|
| Target Classification |
Kinase, Tumor-associated antigen (TAA)
|
ABL2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo27 | Pre-made Human ABL2/ARG/ABLL siRNA oligo Duplex | 27 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo304883 | Pre-made Rat Abl2/Arg/Abll siRNA oligo Duplex | 304883 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11352 | Pre-made Mouse Abl2/Arg/Abll siRNA oligo Duplex | 11352 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717037 | Pre-made Cynomolgus/Rhesus macaque ABL2 siRNA oligo Duplex | 717037 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080757 | Pre-made Cat/Feline ABL2 siRNA oligo Duplex | 101080757 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480052 | Pre-made Dog/Canine ABL2 siRNA oligo Duplex | 480052 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo511845 | Pre-made Bovines/Cattle ABL2/ABLL siRNA oligo Duplex | 511845 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053033 | Pre-made Equine/Horse ABL2 siRNA oligo Duplex | 100053033 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ABL2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T83009-Ab | Human | Anti-Human ABL2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T83009-Ab | Rat | Anti-Rat ABL2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T83009-Ab | Mouse | Anti-Mouse ABL2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T83009-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ABL2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T83009-Ab | Cat/Feline | Anti-Cat/Feline ABL2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T83009-Ab | Dog/Canine | Anti-Dog/Canine ABL2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T83009-Ab | Bovines/Cattle | Anti-Bovines/Cattle ABL2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T83009-Ab | Equine/Horse | Anti-Equine/Horse ABL2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
ABL2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T83009-Ag | Human | Human ABL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T83009-Ag | Rat | Rat ABL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T83009-Ag | Mouse | Mouse ABL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T83009-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ABL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T83009-Ag | Cat/Feline | Cat/Feline ABL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T83009-Ag | Dog/Canine | Dog/Canine ABL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T83009-Ag | Bovines/Cattle | Bovines/Cattle ABL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T83009-Ag | Equine/Horse | Equine/Horse ABL2 recombinant protein | Mammalian cell | Detail |
