Explore GRP94/HSP90B1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15. [provided by RefSeq, Aug 2012]
| Target ID |
GM-T81311
|
| Target Name |
GRP94/HSP90B1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7184
|
| Gene ID |
100033933 (Equus caballus), 101082249 (Felis catus), 22027 (Mus musculus), 282646 (Bos taurus)
362862 (Rattus norvegicus), 404019 (Canis lupus familiaris), 699568 (Macaca mulatta), 7184 (Homo sapiens)
|
| Target Alternative Names |
HSP90B1,Hsp90b1,TRA1,gp96,GRP94,TA-3,Tra1,ERp99,Targ2,Tra-1,endoplasmin,Grp94,ECGP,GP96,HEL35,HEL-S-125m
|
| Uniprot Accession |
P08113,Q95M18,Q66HD0,P41148,P14625
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
Prostate Cancer
|
| Disease from KEGG |
Protein processing in endoplasmic reticulum, PI3K-Akt signaling pathway, IL-17 signaling pathway, Thyroid hormone synthesis, Pathways in cancer, Chemical carcinogenesis - receptor activation, Prostate cancer, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000010610, ENSMUSG00000020048, ENSBTAG00000003362, ENSCAFG00845010421, ENSMMUG00000023469, ENSG00000166598
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of GRP94/HSP90B1 cDNA Clones/ORF Plasmid
GRP94/HSP90B1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7184 | Pre-made Human HSP90B1/ECGP/GP96 siRNA oligo Duplex | 7184 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362862 | Pre-made Rat Hsp90b1/Tra1/Grp94 siRNA oligo Duplex | 362862 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo22027 | Pre-made Mouse Hsp90b1/TA-3/Tra1 siRNA oligo Duplex | 22027 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699568 | Pre-made Cynomolgus/Rhesus macaque HSP90B1 siRNA oligo Duplex | 699568 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101082249 | Pre-made Cat/Feline HSP90B1 siRNA oligo Duplex | 101082249 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo404019 | Pre-made Dog/Canine HSP90B1/TRA1/GRP94 siRNA oligo Duplex | 404019 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282646 | Pre-made Bovines/Cattle HSP90B1/TRA1 siRNA oligo Duplex | 282646 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100033933 | Pre-made Equine/Horse HSP90B1/TRA1/gp96 siRNA oligo Duplex | 100033933 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GRP94/HSP90B1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T81311-Ab | Human | Anti-Human GRP94/HSP90B1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T81311-Ab | Rat | Anti-Rat GRP94/HSP90B1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T81311-Ab | Mouse | Anti-Mouse GRP94/HSP90B1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T81311-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GRP94/HSP90B1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T81311-Ab | Cat/Feline | Anti-Cat/Feline GRP94/HSP90B1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T81311-Ab | Dog/Canine | Anti-Dog/Canine GRP94/HSP90B1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T81311-Ab | Bovines/Cattle | Anti-Bovines/Cattle GRP94/HSP90B1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T81311-Ab | Equine/Horse | Anti-Equine/Horse GRP94/HSP90B1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GRP94/HSP90B1 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T81311-Ag | Human | Human GRP94/HSP90B1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T81311-Ag | Rat | Rat GRP94/HSP90B1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T81311-Ag | Mouse | Mouse GRP94/HSP90B1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T81311-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GRP94/HSP90B1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T81311-Ag | Cat/Feline | Cat/Feline GRP94/HSP90B1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T81311-Ag | Dog/Canine | Dog/Canine GRP94/HSP90B1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T81311-Ag | Bovines/Cattle | Bovines/Cattle GRP94/HSP90B1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T81311-Ag | Equine/Horse | Equine/Horse GRP94/HSP90B1 VLP (virus-like particle) | HEK293 | Products Developing |
