Explore DSG3 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris. [provided by RefSeq, Jan 2016]
| Target ID |
GM-T81281
|
| Target Name |
DSG3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1830
|
| Gene ID |
100065984 (Equus caballus), 101087877 (Felis catus), 13512 (Mus musculus), 1830 (Homo sapiens)
291752 (Rattus norvegicus), 403470 (Canis lupus familiaris), 529902 (Bos taurus), 705685 (Macaca mulatta)
|
| Target Alternative Names |
130 kDa pemphigus vulgaris antigen (PVA),ABOLM,CDHF6,Cadherin family member 6,DSG3,Desmoglein-3,Dsg3,PVA,bal
|
| Uniprot Accession |
O35902,P32926,Q7YRU7
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSECAG00000044697, ENSMUSG00000056632, ENSG00000134757, ENSCAFG00845010787, ENSBTAG00000039483, ENSMMUG00000021094
|
DSG3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1830 | Pre-made Human DSG3/PVA/ABOLM siRNA oligo Duplex | 1830 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo291752 | Pre-made Rat Dsg3 siRNA oligo Duplex | 291752 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13512 | Pre-made Mouse Dsg3/bal siRNA oligo Duplex | 13512 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705685 | Pre-made Cynomolgus/Rhesus macaque DSG3 siRNA oligo Duplex | 705685 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087877 | Pre-made Cat/Feline DSG3 siRNA oligo Duplex | 101087877 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403470 | Pre-made Dog/Canine DSG3 siRNA oligo Duplex | 403470 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo529902 | Pre-made Bovines/Cattle DSG3 siRNA oligo Duplex | 529902 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100065984 | Pre-made Equine/Horse DSG3 siRNA oligo Duplex | 100065984 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DSG3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T81281-Ab | Human | Anti-Human DSG3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T81281-Ab | Rat | Anti-Rat DSG3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T81281-Ab | Mouse | Anti-Mouse DSG3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T81281-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DSG3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T81281-Ab | Cat/Feline | Anti-Cat/Feline DSG3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T81281-Ab | Dog/Canine | Anti-Dog/Canine DSG3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T81281-Ab | Bovines/Cattle | Anti-Bovines/Cattle DSG3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T81281-Ab | Equine/Horse | Anti-Equine/Horse DSG3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
DSG3 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T81281-Ag | Human | Human DSG3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T81281-Ag | Rat | Rat DSG3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T81281-Ag | Mouse | Mouse DSG3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T81281-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DSG3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T81281-Ag | Cat/Feline | Cat/Feline DSG3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T81281-Ag | Dog/Canine | Dog/Canine DSG3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T81281-Ag | Bovines/Cattle | Bovines/Cattle DSG3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T81281-Ag | Equine/Horse | Equine/Horse DSG3 VLP (virus-like particle) | HEK293 | Products Developing |
