Explore VEGFR2/KDR/CD309 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
| Target ID |
GM-T80975
|
| Target Name |
VEGFR2/KDR/CD309
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3791
|
| Gene ID |
100033959 (Equus caballus), 101090260 (Felis catus), 16542 (Mus musculus), 25589 (Rattus norvegicus)
3791 (Homo sapiens), 407170 (Bos taurus), 482154 (Canis lupus familiaris), 698293 (Macaca mulatta)
|
| Target Alternative Names |
6130401C07,CD309,FLK,FLK-1,FLK1,Fetal liver kinase 1 (FLK-1),Flk-1,Flk1,KDR,Kdr,Kinase insert domain receptor (KDR),Krd-1,Ly73,Protein-tyrosine kinase receptor flk-1,VEGFR,VEGFR-2,VEGFR2,Vascular endothelial growth factor receptor 2,Vegfr-2,flk-1,orv,sVEGFR-2
|
| Uniprot Accession |
P35918,O08775,P35968
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
EGFR tyrosine kinase inhibitor resistance, MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Proteoglycans in cancer, Fluid shear stress and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000019429, ENSMUSG00000062960, ENSG00000128052, ENSBTAG00000000782, ENSCAFG00845012083, ENSMMUG00000012669
|
| Target Classification |
Cytokine Receptor, Kinase, Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
Pre-made viral vector of VEGFR2/KDR/CD309 cDNA Clones/ORF Plasmid
VEGFR2/KDR/CD309 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3791 | Pre-made Human KDR/FLK1/CD309 siRNA oligo Duplex | 3791 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25589 | Pre-made Rat Kdr/Vegfr-2 siRNA oligo Duplex | 25589 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16542 | Pre-made Mouse Kdr/orv/Flk1 siRNA oligo Duplex | 16542 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698293 | Pre-made Cynomolgus/Rhesus macaque KDR/FLK-1 siRNA oligo Duplex | 698293 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090260 | Pre-made Cat/Feline KDR siRNA oligo Duplex | 101090260 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482154 | Pre-made Dog/Canine KDR/flk-1 siRNA oligo Duplex | 482154 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo407170 | Pre-made Bovines/Cattle KDR/flk-1/VEGFR2 siRNA oligo Duplex | 407170 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100033959 | Pre-made Equine/Horse KDR/FLK siRNA oligo Duplex | 100033959 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
VEGFR2/KDR/CD309 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T80975-Ab | Human | Anti-Human VEGFR2/KDR/CD309 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T80975-Ab | Rat | Anti-Rat VEGFR2/KDR/CD309 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T80975-Ab | Mouse | Anti-Mouse VEGFR2/KDR/CD309 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T80975-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque VEGFR2/KDR/CD309 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T80975-Ab | Cat/Feline | Anti-Cat/Feline VEGFR2/KDR/CD309 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T80975-Ab | Dog/Canine | Anti-Dog/Canine VEGFR2/KDR/CD309 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T80975-Ab | Bovines/Cattle | Anti-Bovines/Cattle VEGFR2/KDR/CD309 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T80975-Ab | Equine/Horse | Anti-Equine/Horse VEGFR2/KDR/CD309 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
VEGFR2/KDR/CD309 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T80975-Ag | Human | Human VEGFR2/KDR/CD309 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T80975-Ag | Rat | Rat VEGFR2/KDR/CD309 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T80975-Ag | Mouse | Mouse VEGFR2/KDR/CD309 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T80975-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque VEGFR2/KDR/CD309 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T80975-Ag | Cat/Feline | Cat/Feline VEGFR2/KDR/CD309 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T80975-Ag | Dog/Canine | Dog/Canine VEGFR2/KDR/CD309 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T80975-Ag | Bovines/Cattle | Bovines/Cattle VEGFR2/KDR/CD309 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T80975-Ag | Equine/Horse | Equine/Horse VEGFR2/KDR/CD309 VLP (virus-like particle) | HEK293 | Products Developing |
